BRAF V600E MUTATIONS IN METASTATIC MELANOMA - CASE REPORT

The treatment of metastatic melanoma represents a challenge. Vemurafenib, a selective BRAF kinase inhibitor, is a new medicine against carcinoma. Recently, it has been shown that it raises the survival rate among patients with metastatic melanoma who have BRAFV600mutation. This work will discuss new...

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Main Authors: Ivana Inić, Momcilo Inić, Zorka Inić, Milan Zegarac, Aleksandar Martinović, Miomir Šašić, Miloš Bracanović, Gordana Pupić
Format: Article
Language:English
Published: University in Nis, Faculty of Medicine 2014-09-01
Series:Acta Medica Medianae
Subjects:
Online Access:http://publisher.medfak.ni.ac.rs/2014-html/3-broj/Ivana%20Inic-BRAF.pdf
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author Ivana Inić
Momcilo Inić
Zorka Inić
Milan Zegarac
Aleksandar Martinović
Miomir Šašić
Miloš Bracanović
Gordana Pupić
author_facet Ivana Inić
Momcilo Inić
Zorka Inić
Milan Zegarac
Aleksandar Martinović
Miomir Šašić
Miloš Bracanović
Gordana Pupić
author_sort Ivana Inić
collection DOAJ
description The treatment of metastatic melanoma represents a challenge. Vemurafenib, a selective BRAF kinase inhibitor, is a new medicine against carcinoma. Recently, it has been shown that it raises the survival rate among patients with metastatic melanoma who have BRAFV600mutation. This work will discuss new approaches to the treatment of patients with metastatic melanoma, who have been proved to have BRAF V600 mutation and we will present the case of a female patient with whom the clinical study with Vemurafenib has been started.
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spelling doaj.art-5228c4373799444ebccd9d6eee2a08db2022-12-22T00:38:22ZengUniversity in Nis, Faculty of MedicineActa Medica Medianae0365-44781821-27942014-09-01533394110.5633/amm.2014.0306BRAF V600E MUTATIONS IN METASTATIC MELANOMA - CASE REPORTIvana Inić0Momcilo Inić1Zorka Inić2Milan Zegarac3Aleksandar Martinović4Miomir Šašić5Miloš Bracanović6Gordana Pupić7Institute for Oncology and Radiology of Serbia, Belgrade, SerbiaInstitute for Oncology and Radiology of Serbia, Belgrade, SerbiaInstitute for Oncology and Radiology of Serbia, Belgrade, SerbiaInstitute for Oncology and Radiology of Serbia, Belgrade, SerbiaInstitute for Oncology and Radiology of Serbia, Belgrade, SerbiaInstitute for Oncology and Radiology of Serbia, Belgrade, SerbiaClinic for Emergency Surgery, Clinical Center of Serbia, Belgrade, SerbiaInstitute for Oncology and Radiology of Serbia, Belgrade, SerbiaThe treatment of metastatic melanoma represents a challenge. Vemurafenib, a selective BRAF kinase inhibitor, is a new medicine against carcinoma. Recently, it has been shown that it raises the survival rate among patients with metastatic melanoma who have BRAFV600mutation. This work will discuss new approaches to the treatment of patients with metastatic melanoma, who have been proved to have BRAF V600 mutation and we will present the case of a female patient with whom the clinical study with Vemurafenib has been started.http://publisher.medfak.ni.ac.rs/2014-html/3-broj/Ivana%20Inic-BRAF.pdfmetastatic melanomaBRAF V600 mutationtreatment
spellingShingle Ivana Inić
Momcilo Inić
Zorka Inić
Milan Zegarac
Aleksandar Martinović
Miomir Šašić
Miloš Bracanović
Gordana Pupić
BRAF V600E MUTATIONS IN METASTATIC MELANOMA - CASE REPORT
Acta Medica Medianae
metastatic melanoma
BRAF V600 mutation
treatment
title BRAF V600E MUTATIONS IN METASTATIC MELANOMA - CASE REPORT
title_full BRAF V600E MUTATIONS IN METASTATIC MELANOMA - CASE REPORT
title_fullStr BRAF V600E MUTATIONS IN METASTATIC MELANOMA - CASE REPORT
title_full_unstemmed BRAF V600E MUTATIONS IN METASTATIC MELANOMA - CASE REPORT
title_short BRAF V600E MUTATIONS IN METASTATIC MELANOMA - CASE REPORT
title_sort braf v600e mutations in metastatic melanoma case report
topic metastatic melanoma
BRAF V600 mutation
treatment
url http://publisher.medfak.ni.ac.rs/2014-html/3-broj/Ivana%20Inic-BRAF.pdf
work_keys_str_mv AT ivanainic brafv600emutationsinmetastaticmelanomacasereport
AT momciloinic brafv600emutationsinmetastaticmelanomacasereport
AT zorkainic brafv600emutationsinmetastaticmelanomacasereport
AT milanzegarac brafv600emutationsinmetastaticmelanomacasereport
AT aleksandarmartinovic brafv600emutationsinmetastaticmelanomacasereport
AT miomirsasic brafv600emutationsinmetastaticmelanomacasereport
AT milosbracanovic brafv600emutationsinmetastaticmelanomacasereport
AT gordanapupic brafv600emutationsinmetastaticmelanomacasereport