Effects of Physiological and Pathological Urea Concentrations on Human Microvascular Endothelial Cells

Effects of Physiological and Pathological Urea Concentrations on Human Microvascular Endothelial Cells

Urea is the uremic toxin accumulating with the highest concentration in the plasma of chronic kidney disease (CKD) patients, not being completely cleared by dialysis. Urea accumulation is reported to exert direct and indirect side effects on the gastrointestinal tract, kidneys, adipocytes, and cardi...

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Bibliographic Details
Main Authors: Graziano Colombo, Alessandra Altomare, Emanuela Astori, Lucia Landoni, Maria Lisa Garavaglia, Ranieri Rossi, Daniela Giustarini, Maria Chiara Lionetti, Nicoletta Gagliano, Aldo Milzani, Isabella Dalle-Donne
Format: Article
Language:English
Published: MDPI AG 2022-12-01
Series:International Journal of Molecular Sciences
Subjects:
urea
HMEC-1
CVD
CKD
vasorin
differential proteomics
Online Access:https://www.mdpi.com/1422-0067/24/1/691

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https://www.mdpi.com/1422-0067/24/1/691

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