Experience of deceased donor kidney transplantation in Brest region

Introduction : Renal transplantation has progressively increased, and it is the best management of end-stage renal disease. Aim of the research: To evaluate the outcome of renal transplantation from deceased donors to adults living in a region with a population of about one and a half million....

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Main Authors: Katsiaryna Skachykouskaya, Andrej Shestiuk, Siarhei Panko, Aliaksandr Karpitski, Gennadij Zhurbenko
Format: Article
Language:English
Published: Termedia Publishing House 2016-01-01
Series:Studia Medyczne
Subjects:
Online Access:http://www.termedia.pl/Experience-of-deceased-donor-kidney-transplantation-in-Brest-region,67,26459,1,1.html
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author Katsiaryna Skachykouskaya
Andrej Shestiuk
Siarhei Panko
Aliaksandr Karpitski
Gennadij Zhurbenko
author_facet Katsiaryna Skachykouskaya
Andrej Shestiuk
Siarhei Panko
Aliaksandr Karpitski
Gennadij Zhurbenko
author_sort Katsiaryna Skachykouskaya
collection DOAJ
description Introduction : Renal transplantation has progressively increased, and it is the best management of end-stage renal disease. Aim of the research: To evaluate the outcome of renal transplantation from deceased donors to adults living in a region with a population of about one and a half million. Material and methods: A retrospective analysis of the outcomes of 126 recipients of allografts in the period 2011–2014 was performed. The mean age of the recipients was 44.5 ±13.4 years; 71 were male and 55 were female. Kaplan-Meier survival curves were used to assess the graft and recipient survival rates. Results: The overall mortality rate in our study was 4.7% (6 patients), and the mortality of patients with a functioning kidney graft was 3.9% (5 patients). All of them died due to multiple organ failure caused by septic complications of different aetiologies. The data of in our study show that 1-year and 3-year cumulative patient survival after transplantation was 96% and 93.5%, respectively, and the survival rate of kidney grafts was 93% and 68%, respectively. Mean time spent on the renal transplant waiting list had been 31.6 ±7.9 years before the start of the Regional Department of Transplantation, and that was 21.4 ±10.3 (1–141) months in 2014. Conclusions: Three-years of transplant activity in the Brest region resulted in a significant increase in the availability of deceased donor transplantations since every third of the patients with chronic renal failure had kidney allograft transplantation. The 3-year patient survival after transplantation was over 90% owing to up-to-date immunosuppressive regimens and management of postoperative complications.
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spelling doaj.art-522a90306ebf4248a82fe5cd32f08e102022-12-22T00:57:47ZengTermedia Publishing HouseStudia Medyczne1899-18742300-67222016-01-0131425726110.5114/ms.2015.5666726459Experience of deceased donor kidney transplantation in Brest regionKatsiaryna SkachykouskayaAndrej ShestiukSiarhei PankoAliaksandr KarpitskiGennadij ZhurbenkoIntroduction : Renal transplantation has progressively increased, and it is the best management of end-stage renal disease. Aim of the research: To evaluate the outcome of renal transplantation from deceased donors to adults living in a region with a population of about one and a half million. Material and methods: A retrospective analysis of the outcomes of 126 recipients of allografts in the period 2011–2014 was performed. The mean age of the recipients was 44.5 ±13.4 years; 71 were male and 55 were female. Kaplan-Meier survival curves were used to assess the graft and recipient survival rates. Results: The overall mortality rate in our study was 4.7% (6 patients), and the mortality of patients with a functioning kidney graft was 3.9% (5 patients). All of them died due to multiple organ failure caused by septic complications of different aetiologies. The data of in our study show that 1-year and 3-year cumulative patient survival after transplantation was 96% and 93.5%, respectively, and the survival rate of kidney grafts was 93% and 68%, respectively. Mean time spent on the renal transplant waiting list had been 31.6 ±7.9 years before the start of the Regional Department of Transplantation, and that was 21.4 ±10.3 (1–141) months in 2014. Conclusions: Three-years of transplant activity in the Brest region resulted in a significant increase in the availability of deceased donor transplantations since every third of the patients with chronic renal failure had kidney allograft transplantation. The 3-year patient survival after transplantation was over 90% owing to up-to-date immunosuppressive regimens and management of postoperative complications.http://www.termedia.pl/Experience-of-deceased-donor-kidney-transplantation-in-Brest-region,67,26459,1,1.htmlrenal transplantation patient survival graft failure
spellingShingle Katsiaryna Skachykouskaya
Andrej Shestiuk
Siarhei Panko
Aliaksandr Karpitski
Gennadij Zhurbenko
Experience of deceased donor kidney transplantation in Brest region
Studia Medyczne
renal transplantation
patient survival
graft failure
title Experience of deceased donor kidney transplantation in Brest region
title_full Experience of deceased donor kidney transplantation in Brest region
title_fullStr Experience of deceased donor kidney transplantation in Brest region
title_full_unstemmed Experience of deceased donor kidney transplantation in Brest region
title_short Experience of deceased donor kidney transplantation in Brest region
title_sort experience of deceased donor kidney transplantation in brest region
topic renal transplantation
patient survival
graft failure
url http://www.termedia.pl/Experience-of-deceased-donor-kidney-transplantation-in-Brest-region,67,26459,1,1.html
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