Probiotics: a new or an old concept?
Probiotics are an agent renewable from the outside that is capable of delivering active factors (metabolites, regulatory molecules, etc.) to target points of the gastrointestinal tract, and ensure the formation of a regulatory impact source for extraintestinal effects (target points). The uniqueness...
| Main Author: | |
|---|---|
| Format: | Article |
| Language: | Russian |
| Published: |
Remedium Group LLC
2018-10-01
|
| Series: | Медицинский совет |
| Subjects: | |
| Online Access: | https://www.med-sovet.pro/jour/article/view/2652 |
| _version_ | 1797842034738855936 |
|---|---|
| author | S. M. Zakharenko |
| author_facet | S. M. Zakharenko |
| author_sort | S. M. Zakharenko |
| collection | DOAJ |
| description | Probiotics are an agent renewable from the outside that is capable of delivering active factors (metabolites, regulatory molecules, etc.) to target points of the gastrointestinal tract, and ensure the formation of a regulatory impact source for extraintestinal effects (target points). The uniqueness of probiotics lies in the fact that the microbial cell is simultaneously a proper transport container, a delivery system with a specific distribution in the gastrointestinal tract and a factory for reproduction of effector molecules.The modern Probiotics 2.0 concept implies not only the development of bioengineering strains, but the use of probiotics for the maximally proven indications. Conducting research in the most promising areas of probiotics usage, on the one hand, and the development of evidence base for a particular strain in a relatively narrow spectrum of clinically significant effects, on the other hand, significantly reduces the financial and time costs to bring new products to market. An example is a strain of Bifidobacterium longum longum 35624® that was authorized for the treatment of patients with irritable bowel syndrome. However, the “old” probiotics are no less important, especially if the original strain compliance with the “10 golden rules for probiotic therapy” is high. |
| first_indexed | 2024-04-09T16:41:21Z |
| format | Article |
| id | doaj.art-522b13affa1d40708c5e98ee9da51ed8 |
| institution | Directory Open Access Journal |
| issn | 2079-701X 2658-5790 |
| language | Russian |
| last_indexed | 2024-04-09T16:41:21Z |
| publishDate | 2018-10-01 |
| publisher | Remedium Group LLC |
| record_format | Article |
| series | Медицинский совет |
| spelling | doaj.art-522b13affa1d40708c5e98ee9da51ed82023-04-23T06:56:40ZrusRemedium Group LLCМедицинский совет2079-701X2658-57902018-10-01014566010.21518/2079-701X-2018-14-56-602604Probiotics: a new or an old concept?S. M. Zakharenko0Kirov Military Medical Academy, Federal State Budget Military Educational Institution of Higher Education of the Ministry of Defence of the Russian FederationProbiotics are an agent renewable from the outside that is capable of delivering active factors (metabolites, regulatory molecules, etc.) to target points of the gastrointestinal tract, and ensure the formation of a regulatory impact source for extraintestinal effects (target points). The uniqueness of probiotics lies in the fact that the microbial cell is simultaneously a proper transport container, a delivery system with a specific distribution in the gastrointestinal tract and a factory for reproduction of effector molecules.The modern Probiotics 2.0 concept implies not only the development of bioengineering strains, but the use of probiotics for the maximally proven indications. Conducting research in the most promising areas of probiotics usage, on the one hand, and the development of evidence base for a particular strain in a relatively narrow spectrum of clinically significant effects, on the other hand, significantly reduces the financial and time costs to bring new products to market. An example is a strain of Bifidobacterium longum longum 35624® that was authorized for the treatment of patients with irritable bowel syndrome. However, the “old” probiotics are no less important, especially if the original strain compliance with the “10 golden rules for probiotic therapy” is high.https://www.med-sovet.pro/jour/article/view/2652probioticbifidobacterium longum longum 35624s. boulardii |
| spellingShingle | S. M. Zakharenko Probiotics: a new or an old concept? Медицинский совет probiotic bifidobacterium longum longum 35624 s. boulardii |
| title | Probiotics: a new or an old concept? |
| title_full | Probiotics: a new or an old concept? |
| title_fullStr | Probiotics: a new or an old concept? |
| title_full_unstemmed | Probiotics: a new or an old concept? |
| title_short | Probiotics: a new or an old concept? |
| title_sort | probiotics a new or an old concept |
| topic | probiotic bifidobacterium longum longum 35624 s. boulardii |
| url | https://www.med-sovet.pro/jour/article/view/2652 |
| work_keys_str_mv | AT smzakharenko probioticsaneworanoldconcept |