Recent Advances and Promises in Nitrile Hydratase: From Mechanism to Industrial Applications

Recent Advances and Promises in Nitrile Hydratase: From Mechanism to Industrial Applications

Nitrile hydratase (NHase, EC 4.2.1.84) is one type of metalloenzyme participating in the biotransformation of nitriles into amides. Given its catalytic specificity in amide production and eco-friendliness, NHase has overwhelmed its chemical counterpart during the past few decades. However, unclear c...

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Bibliographic Details
Main Authors: Zhongyi Cheng, Yuanyuan Xia, Zhemin Zhou
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-04-01
Series:Frontiers in Bioengineering and Biotechnology
Subjects:
Nitrile hydratase
natural distribution
gene types
catalytic mechanism
post-translational modification
thermostability
Online Access:https://www.frontiersin.org/article/10.3389/fbioe.2020.00352/full

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