Nucleophilic arylation with tetraarylphosphonium salts
Carbon based nucleophiles often are synthetically limited by the high basicity/reactivity of the starting materials. Here, the authors show that tetraarylphosphonium salts can be induced to act as C-aryl nucleophiles for the addition to carbonyls and imines.
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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Nature Portfolio
2016-01-01
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| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/ncomms10337 |
| _version_ | 1818843877108350976 |
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| author | Zuyong Deng Jin-Hong Lin Ji-Chang Xiao |
| author_facet | Zuyong Deng Jin-Hong Lin Ji-Chang Xiao |
| author_sort | Zuyong Deng |
| collection | DOAJ |
| description | Carbon based nucleophiles often are synthetically limited by the high basicity/reactivity of the starting materials. Here, the authors show that tetraarylphosphonium salts can be induced to act as C-aryl nucleophiles for the addition to carbonyls and imines. |
| first_indexed | 2024-12-19T05:04:51Z |
| format | Article |
| id | doaj.art-522ce9be7ee44a2eab0f0182ecda83ba |
| institution | Directory Open Access Journal |
| issn | 2041-1723 |
| language | English |
| last_indexed | 2024-12-19T05:04:51Z |
| publishDate | 2016-01-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Nature Communications |
| spelling | doaj.art-522ce9be7ee44a2eab0f0182ecda83ba2022-12-21T20:34:58ZengNature PortfolioNature Communications2041-17232016-01-01711810.1038/ncomms10337Nucleophilic arylation with tetraarylphosphonium saltsZuyong Deng0Jin-Hong Lin1Ji-Chang Xiao2Key Laboratory of Organofluorine Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of SciencesKey Laboratory of Organofluorine Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of SciencesKey Laboratory of Organofluorine Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of SciencesCarbon based nucleophiles often are synthetically limited by the high basicity/reactivity of the starting materials. Here, the authors show that tetraarylphosphonium salts can be induced to act as C-aryl nucleophiles for the addition to carbonyls and imines.https://doi.org/10.1038/ncomms10337 |
| spellingShingle | Zuyong Deng Jin-Hong Lin Ji-Chang Xiao Nucleophilic arylation with tetraarylphosphonium salts Nature Communications |
| title | Nucleophilic arylation with tetraarylphosphonium salts |
| title_full | Nucleophilic arylation with tetraarylphosphonium salts |
| title_fullStr | Nucleophilic arylation with tetraarylphosphonium salts |
| title_full_unstemmed | Nucleophilic arylation with tetraarylphosphonium salts |
| title_short | Nucleophilic arylation with tetraarylphosphonium salts |
| title_sort | nucleophilic arylation with tetraarylphosphonium salts |
| url | https://doi.org/10.1038/ncomms10337 |
| work_keys_str_mv | AT zuyongdeng nucleophilicarylationwithtetraarylphosphoniumsalts AT jinhonglin nucleophilicarylationwithtetraarylphosphoniumsalts AT jichangxiao nucleophilicarylationwithtetraarylphosphoniumsalts |