Health-Related Quality of Life in Women With Breast Cancer Undergoing Treatment With Hormonal Therapy – A Review Study

This review aimed to analyze the significance and impact of health-related quality of life (QoL) in women with breast cancer undergoing treatment with hormonal therapy. This study developed a comprehensive, structured, systematic search strategy to identify literature related to health and QoL in br...

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Main Author: Lamya Alnaim
Format: Article
Language:English
Published: Galenos Publishing House 2022-10-01
Series:European Journal of Breast Health
Subjects:
Online Access: http://www.eurjbreasthealth.com/archives/archive-detail/article-preview/health-related-quality-of-life-in-women-with-breas/53087
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author Lamya Alnaim
author_facet Lamya Alnaim
author_sort Lamya Alnaim
collection DOAJ
description This review aimed to analyze the significance and impact of health-related quality of life (QoL) in women with breast cancer undergoing treatment with hormonal therapy. This study developed a comprehensive, structured, systematic search strategy to identify literature related to health and QoL in breast cancer patients undergoing treatment with hormonal therapy. The search was conducted for published literature indexed in PubMed (Medline), Cancer Lit, CINAHL, Google Scholar, and Web of Science between 2010 and 2020. Patients associated with the study of QoL reported some difficulties in terms of depression, anxiety, chronic fatigue, sleep problems, pain, sexual dysfunction and sleep disorders. Endocrine-related symptoms did not fluctuate between interventions and remained unchanged in all groups. The evaluation of FACT-G scores (physical well-being subscale) showed statistically significant differences among participants receiving anastrozole versus tamoxifen and exemestane. It can be concluded that the QoL of postmenopausal women with breast cancer is affected by the long-term use of adjuvant endocrine therapy, with difference reported associated with the different therapies. However, further efforts are required to improve QoL instruments and the quantitative evaluation of QoL data for patients receiving adjuvant ET.
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spelling doaj.art-522d30161a67410a89e0e46f5c3abb5e2023-02-15T16:09:02ZengGalenos Publishing HouseEuropean Journal of Breast Health2587-08312022-10-0118429229810.4274/ejbh.galenos.2022.2022-5-813049054Health-Related Quality of Life in Women With Breast Cancer Undergoing Treatment With Hormonal Therapy – A Review StudyLamya Alnaim0 Department of Clinical Pharmacy, College of Pharmacy, King Saud University, Riyadh, Saudi Arabia This review aimed to analyze the significance and impact of health-related quality of life (QoL) in women with breast cancer undergoing treatment with hormonal therapy. This study developed a comprehensive, structured, systematic search strategy to identify literature related to health and QoL in breast cancer patients undergoing treatment with hormonal therapy. The search was conducted for published literature indexed in PubMed (Medline), Cancer Lit, CINAHL, Google Scholar, and Web of Science between 2010 and 2020. Patients associated with the study of QoL reported some difficulties in terms of depression, anxiety, chronic fatigue, sleep problems, pain, sexual dysfunction and sleep disorders. Endocrine-related symptoms did not fluctuate between interventions and remained unchanged in all groups. The evaluation of FACT-G scores (physical well-being subscale) showed statistically significant differences among participants receiving anastrozole versus tamoxifen and exemestane. It can be concluded that the QoL of postmenopausal women with breast cancer is affected by the long-term use of adjuvant endocrine therapy, with difference reported associated with the different therapies. However, further efforts are required to improve QoL instruments and the quantitative evaluation of QoL data for patients receiving adjuvant ET. http://www.eurjbreasthealth.com/archives/archive-detail/article-preview/health-related-quality-of-life-in-women-with-breas/53087 breast cancerhormonal therapyquality of lifewomen
spellingShingle Lamya Alnaim
Health-Related Quality of Life in Women With Breast Cancer Undergoing Treatment With Hormonal Therapy – A Review Study
European Journal of Breast Health
breast cancer
hormonal therapy
quality of life
women
title Health-Related Quality of Life in Women With Breast Cancer Undergoing Treatment With Hormonal Therapy – A Review Study
title_full Health-Related Quality of Life in Women With Breast Cancer Undergoing Treatment With Hormonal Therapy – A Review Study
title_fullStr Health-Related Quality of Life in Women With Breast Cancer Undergoing Treatment With Hormonal Therapy – A Review Study
title_full_unstemmed Health-Related Quality of Life in Women With Breast Cancer Undergoing Treatment With Hormonal Therapy – A Review Study
title_short Health-Related Quality of Life in Women With Breast Cancer Undergoing Treatment With Hormonal Therapy – A Review Study
title_sort health related quality of life in women with breast cancer undergoing treatment with hormonal therapy a review study
topic breast cancer
hormonal therapy
quality of life
women
url http://www.eurjbreasthealth.com/archives/archive-detail/article-preview/health-related-quality-of-life-in-women-with-breas/53087
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