Incidence of Metabolic Syndrome in Patients Admitted to Medical Wards with ST Elevation Myocardial Infarction
Introduction: Metabolic Syndrome (MS) consists of a cluster of metabolic abnormalities that confer exaggerated risk of cardiovascular disease. MS is a novel risk factor for Coronary Artery Disease (CAD) and is a rising disease entity in Asia. Incidence of ST Elevation Myocardial Infarction (STEM...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
JCDR Research and Publications Private Limited
2017-03-01
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| Series: | Journal of Clinical and Diagnostic Research |
| Subjects: | |
| Online Access: | https://jcdr.net/articles/PDF/9481/24803_CE[Ra1]_F(GH)_PF1(SYGH)_PFA(GH)_PF2(NE_SY_DK)%20(1).pdf |
| Summary: | Introduction: Metabolic Syndrome (MS) consists of a cluster
of metabolic abnormalities that confer exaggerated risk of
cardiovascular disease. MS is a novel risk factor for Coronary
Artery Disease (CAD) and is a rising disease entity in Asia.
Incidence of ST Elevation Myocardial Infarction (STEMI) is high
in patients with MS. There is limited data on prevalence of MS in
patients with Acute Myocardial Infarction (AMI).
Aim: To determine frequency of MS in patients admitted with
STEMI.
Materials and Methods: Hundred Consecutive patients between
25 to 75 years who were admitted with STEMI at Govt medical
college Thrissur were included in this prospective study. Subjects
were assessed for five-component conditions of metabolic
syndrome. Criteria to identify MS were based on a “Consensus
statement for diagnosis of metabolic syndrome for Asian Indians”.
Presence of three or more of following suggest MS, Waist
Circumference (WC)>90 cm in men and 80 cm in women, Blood
pressure >130/85 mm Hg, Fasting Plasma Glucose (FPG) >100
mg%, serum triglycerides >150 mg/dl, High Density Lipoprotein
(HDL)<40 mg/dl in male and<50 mg/dl in female. Statistical
analysis was performed using Epi-Info software. Data expressed
as numbers and percents were compared by Chi-square test.
Results: Study enrolled 100 patients (males 80, females 20)
with a mean age of 58. Frequency of MS in patients with STEMI
was 40% (36% of males and 55% of females). Prevalence
of components in the MS group was WC >80/90 -31(71%),
BP>130/85- 23(58%), FPG >100 - 37(93%), HDL <40 (male)/ 50
(female) - 18(45%), TG >150 -15(37.5%).
Conclusion: The present study concluded that there is a
remarkably high occurrence of metabolic syndrome and central
obesity in patients with ST elevation Myocardial Infarction (MI) in
our local population especially in females. Considering this fact
the role of specific and targeted intervention for clinical detection
and management of MS including lifestyle modifications needs to
be addressed. |
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| ISSN: | 2249-782X 0973-709X |