Molecular Backgrounds of ERAP1 Downregulation in Cervical Carcinoma

The antigen processing machinery (APM) plays an important role in immune recognition of virally infected and transformed cells. Defective expression of the APM component ERAP1 is associated with progression and poor clinical outcome in cervical carcinoma. However, the underlying mechanisms of ERAP1...

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Bibliographic Details
Main Authors: Akash M. Mehta, Michelle Osse, Sandra Kolkman-Uljee, Gert Jan Fleuren, Ekaterina S. Jordanova
Format: Article
Language:English
Published: Hindawi Limited 2015-01-01
Series:Analytical Cellular Pathology
Online Access:http://dx.doi.org/10.1155/2015/367837