Effect of Eucalyptus Incense on Prevention of Early and Late Ventilator-associated Pneumonia: A Randomized Controlled Double-blinded Clinical Trial
Background and purpose: Ventilator-associated pneumonia is a common, serious and costly disorder in intensive care units (ICUs) that rank first in hospital infections. So, appropriate interventions are needed to prevent this condition. Eucalyptus is a plant with antibiotic properties, therefore, cur...
| Main Authors: | , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Mazandaran University of Medical Sciences
2019-03-01
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| Series: | Journal of Mazandaran University of Medical Sciences |
| Subjects: | |
| Online Access: | http://jmums.mazums.ac.ir/article-1-11633-en.html |
| _version_ | 1797943847835140096 |
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| author | Masoud Fallahi HasanAli Karimpour Javad AminiSaman Saeed Mohammadi Azam Sharifi Alireza Jahanbakhsh Masoud Modarresi Maryam Mirzaei Rasol Kawyannejad |
| author_facet | Masoud Fallahi HasanAli Karimpour Javad AminiSaman Saeed Mohammadi Azam Sharifi Alireza Jahanbakhsh Masoud Modarresi Maryam Mirzaei Rasol Kawyannejad |
| author_sort | Masoud Fallahi |
| collection | DOAJ |
| description | Background and purpose: Ventilator-associated pneumonia is a common, serious and costly disorder in intensive care units (ICUs) that rank first in hospital infections. So, appropriate interventions are needed to prevent this condition. Eucalyptus is a plant with antibiotic properties, therefore, current study aimed at investigating its effects on prevention of endotracheal tube-associated pneumonia in ICU.
Materials and methods: A double-blind clinical trial was performed in 100 patients with endotracheal tube and on ventilator in ICU in Kermanshah Imam Reza Hospital, Iran. The patients were divided into two groups. In intervention group (n=50) 4 cc of 2% eucalyptus solution was mixed with 6 cc distilled water and in control group (n=50) 10 cc distilled water was given three times daily through a nebulizer kit connected to mechanical ventilation devices. Data on the rate of early and late pneumonia were compared based on CPIS criteria applying t-test and Chi-square.
Results: The incidence of early and late pneumonia was lower in intervention group compared to that of the controls. The decrease was significantly more in onset of late pneumonia (P=0.01). The onset of pneumonia due to mechanical ventilation was significantly higher in intervention group than that of the control group (P=0.01).
Conclusion: Eucalyptus was found to be an effective prophylaxis that could delay the development of pulmonary infection in patients on ventilation. Therefore, it is suggested in ICUs in patients with tracheal tubes.
(Clinical Trials Registry Number: IRCT2017010727819N2) |
| first_indexed | 2024-04-10T20:30:36Z |
| format | Article |
| id | doaj.art-522f78809ba542309ab8830405f6a981 |
| institution | Directory Open Access Journal |
| issn | 1735-9260 1735-9279 |
| language | English |
| last_indexed | 2024-04-10T20:30:36Z |
| publishDate | 2019-03-01 |
| publisher | Mazandaran University of Medical Sciences |
| record_format | Article |
| series | Journal of Mazandaran University of Medical Sciences |
| spelling | doaj.art-522f78809ba542309ab8830405f6a9812023-01-25T06:58:27ZengMazandaran University of Medical SciencesJournal of Mazandaran University of Medical Sciences1735-92601735-92792019-03-01281706473Effect of Eucalyptus Incense on Prevention of Early and Late Ventilator-associated Pneumonia: A Randomized Controlled Double-blinded Clinical TrialMasoud Fallahi0HasanAli Karimpour1Javad AminiSaman2Saeed Mohammadi3Azam Sharifi4Alireza Jahanbakhsh5Masoud Modarresi6Maryam Mirzaei7Rasol Kawyannejad8 MSc in Nursing, Imam Reza Hospital, Kermanshah University of Medical Sciences, Kermanshah, Iran 2 Assistant Professor, Department of Anesthesiology, School of Medicine, Kermanshah University of Medical Sciences, Kermanshah, Iran 2 Assistant Professor, Department of Anesthesiology, School of Medicine, Kermanshah University of Medical Sciences, Kermanshah, Iran Assistant Professor, Department of Anesthesiology, School of Medicine, Kermanshah University of Medical Sciences, Kermanshah, Iran MSc in Anesthesiology, Department of Nursing, Nahavand School of Allied Medical Sciences, Hamadan University of Medical Sciences, Hamadan, Iran and PhD Student inNursing, Department of Nursing, University of Social Welfare Rehabilitation Sciences, Tehran, Iran Assosiate Professor, Department of Infectious Diseases, School of Medicine, Kermanshah University of Medical Sciences, Kermanshah, Iran Assistant Professor, Department of Pharmacognosy and Pharmaceutical Biotechnology, School of Pharmacy, Kermanshah University of Medical Sciences, Kermanshah, Iran MSc in Epidemiology, Research Assistant, Department of Anesthesiology, School of Allied Medical Sciences, Kermanshah University of Medical Sciences, Kermanshah, Iran Anesthesiology Instructor, Department of Anesthesiology, School of Allied Medical Sciences, Kermanshah University of Medical Sciences, Kermanshah, Iran Background and purpose: Ventilator-associated pneumonia is a common, serious and costly disorder in intensive care units (ICUs) that rank first in hospital infections. So, appropriate interventions are needed to prevent this condition. Eucalyptus is a plant with antibiotic properties, therefore, current study aimed at investigating its effects on prevention of endotracheal tube-associated pneumonia in ICU. Materials and methods: A double-blind clinical trial was performed in 100 patients with endotracheal tube and on ventilator in ICU in Kermanshah Imam Reza Hospital, Iran. The patients were divided into two groups. In intervention group (n=50) 4 cc of 2% eucalyptus solution was mixed with 6 cc distilled water and in control group (n=50) 10 cc distilled water was given three times daily through a nebulizer kit connected to mechanical ventilation devices. Data on the rate of early and late pneumonia were compared based on CPIS criteria applying t-test and Chi-square. Results: The incidence of early and late pneumonia was lower in intervention group compared to that of the controls. The decrease was significantly more in onset of late pneumonia (P=0.01). The onset of pneumonia due to mechanical ventilation was significantly higher in intervention group than that of the control group (P=0.01). Conclusion: Eucalyptus was found to be an effective prophylaxis that could delay the development of pulmonary infection in patients on ventilation. Therefore, it is suggested in ICUs in patients with tracheal tubes. (Clinical Trials Registry Number: IRCT2017010727819N2)http://jmums.mazums.ac.ir/article-1-11633-en.htmlpulmonary infectionmechanical ventilationeucalyptusintensive care unit |
| spellingShingle | Masoud Fallahi HasanAli Karimpour Javad AminiSaman Saeed Mohammadi Azam Sharifi Alireza Jahanbakhsh Masoud Modarresi Maryam Mirzaei Rasol Kawyannejad Effect of Eucalyptus Incense on Prevention of Early and Late Ventilator-associated Pneumonia: A Randomized Controlled Double-blinded Clinical Trial Journal of Mazandaran University of Medical Sciences pulmonary infection mechanical ventilation eucalyptus intensive care unit |
| title | Effect of Eucalyptus Incense on Prevention of Early and Late Ventilator-associated Pneumonia: A Randomized Controlled Double-blinded Clinical Trial |
| title_full | Effect of Eucalyptus Incense on Prevention of Early and Late Ventilator-associated Pneumonia: A Randomized Controlled Double-blinded Clinical Trial |
| title_fullStr | Effect of Eucalyptus Incense on Prevention of Early and Late Ventilator-associated Pneumonia: A Randomized Controlled Double-blinded Clinical Trial |
| title_full_unstemmed | Effect of Eucalyptus Incense on Prevention of Early and Late Ventilator-associated Pneumonia: A Randomized Controlled Double-blinded Clinical Trial |
| title_short | Effect of Eucalyptus Incense on Prevention of Early and Late Ventilator-associated Pneumonia: A Randomized Controlled Double-blinded Clinical Trial |
| title_sort | effect of eucalyptus incense on prevention of early and late ventilator associated pneumonia a randomized controlled double blinded clinical trial |
| topic | pulmonary infection mechanical ventilation eucalyptus intensive care unit |
| url | http://jmums.mazums.ac.ir/article-1-11633-en.html |
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