Treatment duration-dependent efficacy of Japanese cedar pollen sublingual immunotherapy: Evaluation of a phase II/III trial over three pollen dispersal seasons

Treatment duration-dependent efficacy of Japanese cedar pollen sublingual immunotherapy: Evaluation of a phase II/III trial over three pollen dispersal seasons

Background: We conducted a randomized, placebo-controlled, double-blind clinical trial to investigate the optimal dose and long-term efficacy and safety of Japanese cedar (JC) pollen tablets for SLIT (JapicCTI-142579). Here, we report details of the effects of the JC pollen SLIT tablet on rhinitis a...

Full description

Bibliographic Details
Main Authors:	Syuji Yonekura, Minoru Gotoh, Shinya Kaneko, Keishi Kanazawa, Yoshie Takeuji, Kimihiro Okubo, Yoshitaka Okamoto
Format:	Article
Language:	English
Published:	Elsevier 2019-10-01
Series:	Allergology International
Online Access:	http://www.sciencedirect.com/science/article/pii/S1323893019300620

Similar Items

An analysis of factors related to the effect of sublingual immunotherapy on Japanese cedar pollen induced allergic rhinitis
by: Syuji Yonekura, et al.
Published: (2018-04-01)

Japanese cedar pollen sublingual immunotherapy is effective in treating seasonal allergic rhinitis during the pollen dispersal period for Japanese cedar and Japanese cypress
by: Syuji Yonekura, et al.
Published: (2022-01-01)

Efficacy of Japanese cedar pollen sublingual immunotherapy tablets for Japanese cypress pollinosis
by: Tomoya Kurokawa, MD, PhD, et al.
Published: (2023-05-01)

Sublingual Immunotherapy for Japanese Cedar Pollinosis
by: Minoru Gotoh, et al.
Published: (2005-01-01)

Sublingual Immunotherapy for Japanese Cedar Pollinosis
by: Kimihiro Okubo, et al.
Published: (2009-01-01)

Safety profile and immunological response of dual sublingual immunotherapy with house dust mite tablet and Japanese cedar pollen tablet
by: Minoru Gotoh, et al.
Published: (2020-01-01)

A Randomized Double-Blind Comparative Study of Sublingual Immunotherapy for Cedar Pollinosis
by: Kimihiro Okubo, et al.
Published: (2008-01-01)

Effect of Japanese Cedar Pollen Sublingual Immunotherapy on Asthma Patients with Seasonal Allergic Rhinitis Caused by Japanese Cedar Pollen
by: Shoko Ueda, et al.
Published: (2022-03-01)

Investigating Japanese cedar pollen-induced allergic rhinitis and related terms using Google Trends
by: Tomohisa Iinuma, et al.
Published: (2020-10-01)

Immunological parameters in prophylactic sublingual immunotherapy in asymptomatic subjects sensitized to Japanese cedar pollen
by: Kei-ichi Yamanaka, et al.
Published: (2015-01-01)

Long-term treatment of Japanese cedar pollinosis with Japanese cedar pollen SLIT drops and persistence of treatment effect: A post-marketing clinical trial
by: Yasuyuki Nomura, et al.
Published: (2021-01-01)

Complement Factor H Is an Early Predictive Biomarker of the Therapeutic Efficacy of Sublingual Immunotherapy for Japanese Cedar Pollinosis
by: Riyo Yoneda, et al.
Published: (2022-11-01)

Changes of Micro-RNAs in Asymptomatic Subjects Sensitized to Japanese Cedar Pollen after Prophylactic Sublingual Immunotherapy
by: Bo Hou M.D., et al.
Published: (2015-03-01)

Decreased numbers of metachromatic cells in nasal swabs in Japanese cedar pollinosis following sublingual immunotherapy
by: Kuninori Otsuka, et al.
Published: (2020-09-01)

Oral Administration of Heat-Killed Lactobacillus gasseri OLL2809 Reduces Cedar Pollen Antigen-Induced Peritoneal Eosinophilia in Mice
by: Toshihiro Sashihara, et al.
Published: (2008-01-01)

Omalizumab is Effective and Safe in the Treatment of Japanese Cedar Pollen-induced Seasonal Allergic Rhinitis
by: Kimihiro Okubo, et al.
Published: (2006-01-01)

Prolonged effect of allergen sublingual immunotherapy to grass pollen
by: Andrzej Bozek, et al.
Published: (2018-12-01)

Inhibition of the Antigen Provoked Nasal Reaction by Second-generation Antihistamines in Patients with Japanese Cedar Pollinosis
by: Kimihiro Okubo, et al.
Published: (2006-01-01)

Effect of Pollen-Specific Sublingual Immunotherapy on Oral Allergy Syndrome
by: Karl-Christian Bergmann, MD, et al.
Published: (2008-01-01)

Delay of Onset of Symptoms of Japanese Cedar Pollinosis by Treatment with a Leukotriene Receptor Antagonist
by: Minoru Gotoh, et al.
Published: (2011-01-01)

A novel approach of preventing Japanese cedar pollen dispersal that is the cause of Japanese cedar pollinosis (JCP) using pollen-specific fungal infection.
by: Yuuri Hirooka, et al.
Published: (2013-01-01)

Present Situation of Cedar Pollinosis in Japan and its Immune Responses
by: Yoshitaka Okamoto, et al.
Published: (2009-01-01)

Determining Minimal Clinically Important Differences in Japanese Cedar/Cypress Pollinosis Patients
by: Takaya Higaki, et al.
Published: (2013-01-01)

Comparison between sublingual immunotherapy and subcutaneous immunotherapy in the treatment of pollen-induced vernal keratoconjunctivitis in children
by: Basem M Ibrahim, et al.
Published: (2018-01-01)

Effect of fexofenadine on the quality of life of Japanese cedar pollinosis patients
by: Kimihiro Okubo, et al.
Published: (2004-01-01)

Evaluation of quality of life of patients with pollen allergy before and after sublingual immunotherapy course
by: S. O. Zubchenko, et al.
Published: (2018-09-01)

Reduction of Cedar Pollen Adhesion by Lecithin Polymer Coating
by: Yusuke Kobayashi, et al.
Published: (2005-01-01)

Sublingual Immunotherapy for Japanese Cedar Pollinosis: Current Clinical and Research Status
by: Daiju Sakurai, et al.
Published: (2022-11-01)

Plant Food Allergy Improvement after Grass Pollen Sublingual Immunotherapy: A Case Series
by: Fabiana Furci, et al.
Published: (2021-10-01)

Satisfaction with grass pollen sublingual immunotherapy assessed by ESPIA questionnaire – first results from Bulgaria
by: Plamena Novakova, et al.
Published: (2020-08-01)

Sublingual Immunotherapy: How Sublingual Allergen Administration Heals Allergic Diseases; Current Perspective about the Mode of Action
by: Minoru Gotoh, et al.
Published: (2021-02-01)

Continuous 6-Year Follow-Up Study of Sensitization to Japanese Cedar Pollen and Onset in Schoolchildren
by: Atsuko Kanazawa, et al.
Published: (2014-01-01)

Investigation of Cry J1 and Cry J2 Concentrations in Japanese Cedar Pollen and Non-Pollen Seasons
by: Hiroki Tomizawa, et al.
Published: (2022-03-01)

Sublingual Immunotherapy with House Dust Extract for House Dust-Mite Allergic Rhinitis in Children
by: Syuji Yonekura, et al.
Published: (2010-01-01)

Satisfaction and quality of life of allergic patients following sublingual five-grass pollen tablet immunotherapy in Spain
by: Darío Antolín-Amerigo, et al.
Published: (2017-11-01)

The antigenicity and safety of transgenic rice seeds which contain genetically modified Japanese cedar pollen allergens
by: Shinya Takaishi, et al.
Published: (2020-08-01)

Measurement of Japanese Cedar Pollen-Specific IgE in Nasal Secretions
by: Hiroshi Sakaida, et al.
Published: (2014-01-01)

Real-World Adherence and Evidence of Subcutaneous and Sublingual Immunotherapy in Grass and Tree Pollen-Induced Allergic Rhinitis and Asthma
by: Vogelberg C, et al.
Published: (2020-05-01)

A major step forward for sublingual immunotherapy: the quality of 5-grass pollen tablet is recognized also in Italy
by: Ciprandi G
Published: (2015-03-01)

Establishment of enzyme-linked immunosorbent facilitated antigen binding as a biomarker assay for Japanese cedar pollen allergy immunotherapy
by: Chiharu Fukano, et al.
Published: (2019-07-01)