Bioprospecting of the <i>Telekia speciosa</i>: Uncovering the Composition and Biological Properties of Its Essential Oils
The essential oils (EOs) of <i>Telekia speciosa</i>, a perennial plant native to southeastern Europe and Asia Minor, were analyzed for their composition and biological properties. <i>T. speciosa</i> is an invasive plant in Poland; however, its beauty prompts gardeners to cult...
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MDPI AG
2023-05-01
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| Series: | Applied Sciences |
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| Online Access: | https://www.mdpi.com/2076-3417/13/9/5674 |
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| author | Anna Wajs-Bonikowska Łukasz Szoka Paweł Kwiatkowski Surya Nandan Meena Anna Stojakowska |
| author_facet | Anna Wajs-Bonikowska Łukasz Szoka Paweł Kwiatkowski Surya Nandan Meena Anna Stojakowska |
| author_sort | Anna Wajs-Bonikowska |
| collection | DOAJ |
| description | The essential oils (EOs) of <i>Telekia speciosa</i>, a perennial plant native to southeastern Europe and Asia Minor, were analyzed for their composition and biological properties. <i>T. speciosa</i> is an invasive plant in Poland; however, its beauty prompts gardeners to cultivate the plants. <i>T. speciosa</i> serves as a valuable source of nectar and pollen for honey bees. Our results revealed more than 150 compounds in the flower, leaf, and root EOs. Major constituents found in the essential oils from the roots included isoalantolacton (46.2%) and from the flowers nerol (11.9%), while from the leaves, they included (<i>E</i>)-nerolidol (10.1%). <i>T. speciosa</i> flower EO showed significant cytotoxicity against A375 cells, with IC<sub>50</sub> values of 7.2, 5.1, and 3.4 μg/mL referring to 24, 48, and 72 h, respectively, indicating its potential as a natural cytotoxic agent. The antimicrobial activity of the essential oils against <i>Staphylococcus aureus</i> ATCC 29213 and <i>Escherichia coli</i> ATCC 25922 was also investigated. The essential oils from the flowers and leaves of <i>T. speciosa</i> demonstrated higher inhibitory activity against <i>S. aureus</i> (MIC: 5.9–7.8 μL/mL) and <i>E. coli</i> (MIC: 7.8–11.7 μL/mL) than the essential oil isolated from the roots of the plant (MICs 31.3 and 62.5 μL/mL against <i>S. aureus</i> and <i>E. coli</i>, respectively). |
| first_indexed | 2024-03-11T04:23:08Z |
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| institution | Directory Open Access Journal |
| issn | 2076-3417 |
| language | English |
| last_indexed | 2024-03-11T04:23:08Z |
| publishDate | 2023-05-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Applied Sciences |
| spelling | doaj.art-522fe8ecf60a4de695420a86209ccc5b2023-11-17T22:37:16ZengMDPI AGApplied Sciences2076-34172023-05-01139567410.3390/app13095674Bioprospecting of the <i>Telekia speciosa</i>: Uncovering the Composition and Biological Properties of Its Essential OilsAnna Wajs-Bonikowska0Łukasz Szoka1Paweł Kwiatkowski2Surya Nandan Meena3Anna Stojakowska4Institute of Natural Products and Cosmetics, Faculty of Biotechnology and Food Sciences, Łódz University of Technology, Stefanowskiego Street 2/22, 90-537 Łódz, PolandDepartment of Medicinal Chemistry, Division of Laboratory Medicine, Faculty of Pharmacy, Medical University of Białystok, Mickiewicza Street 2D, 15-222 Białystok, PolandDepartment of Diagnostic Immunology, Pomeranian Medical University in Szczecin, Powstańców Wielkopolskich Street 72, 70-111 Szczecin, PolandDepartment of Chemistry, Savitribai Phule Pune University, Pune 411007, IndiaMaj Institute of Pharmacology, Polish Academy of Sciences, 31-343 Kraków, PolandThe essential oils (EOs) of <i>Telekia speciosa</i>, a perennial plant native to southeastern Europe and Asia Minor, were analyzed for their composition and biological properties. <i>T. speciosa</i> is an invasive plant in Poland; however, its beauty prompts gardeners to cultivate the plants. <i>T. speciosa</i> serves as a valuable source of nectar and pollen for honey bees. Our results revealed more than 150 compounds in the flower, leaf, and root EOs. Major constituents found in the essential oils from the roots included isoalantolacton (46.2%) and from the flowers nerol (11.9%), while from the leaves, they included (<i>E</i>)-nerolidol (10.1%). <i>T. speciosa</i> flower EO showed significant cytotoxicity against A375 cells, with IC<sub>50</sub> values of 7.2, 5.1, and 3.4 μg/mL referring to 24, 48, and 72 h, respectively, indicating its potential as a natural cytotoxic agent. The antimicrobial activity of the essential oils against <i>Staphylococcus aureus</i> ATCC 29213 and <i>Escherichia coli</i> ATCC 25922 was also investigated. The essential oils from the flowers and leaves of <i>T. speciosa</i> demonstrated higher inhibitory activity against <i>S. aureus</i> (MIC: 5.9–7.8 μL/mL) and <i>E. coli</i> (MIC: 7.8–11.7 μL/mL) than the essential oil isolated from the roots of the plant (MICs 31.3 and 62.5 μL/mL against <i>S. aureus</i> and <i>E. coli</i>, respectively).https://www.mdpi.com/2076-3417/13/9/5674<i>Telekia speciosa</i>essential oilantimicrobial propertiescytotoxic activitymelliferous plant |
| spellingShingle | Anna Wajs-Bonikowska Łukasz Szoka Paweł Kwiatkowski Surya Nandan Meena Anna Stojakowska Bioprospecting of the <i>Telekia speciosa</i>: Uncovering the Composition and Biological Properties of Its Essential Oils Applied Sciences <i>Telekia speciosa</i> essential oil antimicrobial properties cytotoxic activity melliferous plant |
| title | Bioprospecting of the <i>Telekia speciosa</i>: Uncovering the Composition and Biological Properties of Its Essential Oils |
| title_full | Bioprospecting of the <i>Telekia speciosa</i>: Uncovering the Composition and Biological Properties of Its Essential Oils |
| title_fullStr | Bioprospecting of the <i>Telekia speciosa</i>: Uncovering the Composition and Biological Properties of Its Essential Oils |
| title_full_unstemmed | Bioprospecting of the <i>Telekia speciosa</i>: Uncovering the Composition and Biological Properties of Its Essential Oils |
| title_short | Bioprospecting of the <i>Telekia speciosa</i>: Uncovering the Composition and Biological Properties of Its Essential Oils |
| title_sort | bioprospecting of the i telekia speciosa i uncovering the composition and biological properties of its essential oils |
| topic | <i>Telekia speciosa</i> essential oil antimicrobial properties cytotoxic activity melliferous plant |
| url | https://www.mdpi.com/2076-3417/13/9/5674 |
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