Bioinformatics Accelerates the Major Tetrad: A Real Boost for the Pharmaceutical Industry
With advanced technology and its development, bioinformatics is one of the avant-garde fields that has managed to make amazing progress in the pharmaceutical–medical field by modeling the infrastructural dimensions of healthcare and integrating computing tools in drug innovation, facilitating preven...
| Main Authors: | , , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2021-06-01
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| Series: | International Journal of Molecular Sciences |
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| Online Access: | https://www.mdpi.com/1422-0067/22/12/6184 |
| _version_ | 1797530938088882176 |
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| author | Tapan Behl Ishnoor Kaur Aayush Sehgal Sukhbir Singh Saurabh Bhatia Ahmed Al-Harrasi Gokhan Zengin Elena Emilia Babes Ciprian Brisc Manuela Stoicescu Mirela Marioara Toma Cristian Sava Simona Gabriela Bungau |
| author_facet | Tapan Behl Ishnoor Kaur Aayush Sehgal Sukhbir Singh Saurabh Bhatia Ahmed Al-Harrasi Gokhan Zengin Elena Emilia Babes Ciprian Brisc Manuela Stoicescu Mirela Marioara Toma Cristian Sava Simona Gabriela Bungau |
| author_sort | Tapan Behl |
| collection | DOAJ |
| description | With advanced technology and its development, bioinformatics is one of the avant-garde fields that has managed to make amazing progress in the pharmaceutical–medical field by modeling the infrastructural dimensions of healthcare and integrating computing tools in drug innovation, facilitating prevention, detection/more accurate diagnosis, and treatment of disorders, while saving time and money. By association, bioinformatics and pharmacovigilance promoted both sample analyzes and interpretation of drug side effects, also focusing on drug discovery and development (DDD), in which systems biology, a personalized approach, and drug repositioning were considered together with translational medicine. The role of bioinformatics has been highlighted in DDD, proteomics, genetics, modeling, miRNA discovery and assessment, and clinical genome sequencing. The authors have collated significant data from the most known online databases and publishers, also narrowing the diversified applications, in order to target four major areas (tetrad): DDD, anti-microbial research, genomic sequencing, and miRNA research and its significance in the management of current pandemic context. Our analysis aims to provide optimal data in the field by stratification of the information related to the published data in key sectors and to capture the attention of researchers interested in bioinformatics, a field that has succeeded in advancing the healthcare paradigm by introducing developing techniques and multiple database platforms, addressed in the manuscript. |
| first_indexed | 2024-03-10T10:37:03Z |
| format | Article |
| id | doaj.art-5232fad229de4c78811baa34f9bd77c1 |
| institution | Directory Open Access Journal |
| issn | 1661-6596 1422-0067 |
| language | English |
| last_indexed | 2024-03-10T10:37:03Z |
| publishDate | 2021-06-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | International Journal of Molecular Sciences |
| spelling | doaj.art-5232fad229de4c78811baa34f9bd77c12023-11-21T23:14:15ZengMDPI AGInternational Journal of Molecular Sciences1661-65961422-00672021-06-012212618410.3390/ijms22126184Bioinformatics Accelerates the Major Tetrad: A Real Boost for the Pharmaceutical IndustryTapan Behl0Ishnoor Kaur1Aayush Sehgal2Sukhbir Singh3Saurabh Bhatia4Ahmed Al-Harrasi5Gokhan Zengin6Elena Emilia Babes7Ciprian Brisc8Manuela Stoicescu9Mirela Marioara Toma10Cristian Sava11Simona Gabriela Bungau12Department of Pharmacology, Chitkara College of Pharmacy, Chitkara University, Punjab 140401, IndiaDepartment of Pharmacology, Chitkara College of Pharmacy, Chitkara University, Punjab 140401, IndiaDepartment of Pharmacology, Chitkara College of Pharmacy, Chitkara University, Punjab 140401, IndiaDepartment of Pharmacology, Chitkara College of Pharmacy, Chitkara University, Punjab 140401, IndiaAmity Institute of Pharmacy, Amity University, Gurugram 122413, IndiaNatural & Medical Sciences Research Centre, University of Nizwa, Birkat Al Mauz, Nizwa 616, OmanDepartment of Biology, Faculty of Science, Selcuk University Campus, 42130 Konya, TurkeyDepartment of Medical Disciplines, Faculty of Medicine and Pharmacy, University of Oradea, 410073 Oradea, RomaniaDepartment of Medical Disciplines, Faculty of Medicine and Pharmacy, University of Oradea, 410073 Oradea, RomaniaDepartment of Medical Disciplines, Faculty of Medicine and Pharmacy, University of Oradea, 410073 Oradea, RomaniaDepartment of Pharmacy, Faculty of Medicine and Pharmacy, University of Oradea, 410028 Oradea, RomaniaDepartment of Medical Disciplines, Faculty of Medicine and Pharmacy, University of Oradea, 410073 Oradea, RomaniaDepartment of Pharmacy, Faculty of Medicine and Pharmacy, University of Oradea, 410028 Oradea, RomaniaWith advanced technology and its development, bioinformatics is one of the avant-garde fields that has managed to make amazing progress in the pharmaceutical–medical field by modeling the infrastructural dimensions of healthcare and integrating computing tools in drug innovation, facilitating prevention, detection/more accurate diagnosis, and treatment of disorders, while saving time and money. By association, bioinformatics and pharmacovigilance promoted both sample analyzes and interpretation of drug side effects, also focusing on drug discovery and development (DDD), in which systems biology, a personalized approach, and drug repositioning were considered together with translational medicine. The role of bioinformatics has been highlighted in DDD, proteomics, genetics, modeling, miRNA discovery and assessment, and clinical genome sequencing. The authors have collated significant data from the most known online databases and publishers, also narrowing the diversified applications, in order to target four major areas (tetrad): DDD, anti-microbial research, genomic sequencing, and miRNA research and its significance in the management of current pandemic context. Our analysis aims to provide optimal data in the field by stratification of the information related to the published data in key sectors and to capture the attention of researchers interested in bioinformatics, a field that has succeeded in advancing the healthcare paradigm by introducing developing techniques and multiple database platforms, addressed in the manuscript.https://www.mdpi.com/1422-0067/22/12/6184bioinformaticspharmacovigilancemicrobiologymicroRNACOVID-19public health |
| spellingShingle | Tapan Behl Ishnoor Kaur Aayush Sehgal Sukhbir Singh Saurabh Bhatia Ahmed Al-Harrasi Gokhan Zengin Elena Emilia Babes Ciprian Brisc Manuela Stoicescu Mirela Marioara Toma Cristian Sava Simona Gabriela Bungau Bioinformatics Accelerates the Major Tetrad: A Real Boost for the Pharmaceutical Industry International Journal of Molecular Sciences bioinformatics pharmacovigilance microbiology microRNA COVID-19 public health |
| title | Bioinformatics Accelerates the Major Tetrad: A Real Boost for the Pharmaceutical Industry |
| title_full | Bioinformatics Accelerates the Major Tetrad: A Real Boost for the Pharmaceutical Industry |
| title_fullStr | Bioinformatics Accelerates the Major Tetrad: A Real Boost for the Pharmaceutical Industry |
| title_full_unstemmed | Bioinformatics Accelerates the Major Tetrad: A Real Boost for the Pharmaceutical Industry |
| title_short | Bioinformatics Accelerates the Major Tetrad: A Real Boost for the Pharmaceutical Industry |
| title_sort | bioinformatics accelerates the major tetrad a real boost for the pharmaceutical industry |
| topic | bioinformatics pharmacovigilance microbiology microRNA COVID-19 public health |
| url | https://www.mdpi.com/1422-0067/22/12/6184 |
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