Use of Everolimus to treat cardiac rhabdomyomas and incessant arrhythmias in a newborn: Benefits and complications
We report treating a term neonate with tuberous sclerosis and giant rhabdomyomas who presented with incessant supraventricular tachycardia with Everolimus. The treatment was efficient in reducing tumor size and assisted as an adjunct therapy in controlling arrhythmia and limiting preexcitation. Trea...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2022-01-01
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| Series: | Annals of Pediatric Cardiology |
| Subjects: | |
| Online Access: | http://www.annalspc.com/article.asp?issn=0974-2069;year=2022;volume=15;issue=1;spage=58;epage=60;aulast=Sagiv |
| _version_ | 1818474569968648192 |
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| author | Eyal Sagiv Sathish Mallenahalli Chikkabyrappa Jeffrey Conwell Mark Lewin Terrence Un Hoong Chun |
| author_facet | Eyal Sagiv Sathish Mallenahalli Chikkabyrappa Jeffrey Conwell Mark Lewin Terrence Un Hoong Chun |
| author_sort | Eyal Sagiv |
| collection | DOAJ |
| description | We report treating a term neonate with tuberous sclerosis and giant rhabdomyomas who presented with incessant supraventricular tachycardia with Everolimus. The treatment was efficient in reducing tumor size and assisted as an adjunct therapy in controlling arrhythmia and limiting preexcitation. Treatment was challenged by difficulty to achieve stable drug level and limited by neutropenia as a serious side effect. |
| first_indexed | 2024-04-14T04:39:01Z |
| format | Article |
| id | doaj.art-5233ade2fbe6466196ad17549a4fe670 |
| institution | Directory Open Access Journal |
| issn | 0974-2069 |
| language | English |
| last_indexed | 2024-04-14T04:39:01Z |
| publishDate | 2022-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Annals of Pediatric Cardiology |
| spelling | doaj.art-5233ade2fbe6466196ad17549a4fe6702022-12-22T02:11:46ZengWolters Kluwer Medknow PublicationsAnnals of Pediatric Cardiology0974-20692022-01-01151586010.4103/apc.apc_11_21Use of Everolimus to treat cardiac rhabdomyomas and incessant arrhythmias in a newborn: Benefits and complicationsEyal SagivSathish Mallenahalli ChikkabyrappaJeffrey ConwellMark LewinTerrence Un Hoong ChunWe report treating a term neonate with tuberous sclerosis and giant rhabdomyomas who presented with incessant supraventricular tachycardia with Everolimus. The treatment was efficient in reducing tumor size and assisted as an adjunct therapy in controlling arrhythmia and limiting preexcitation. Treatment was challenged by difficulty to achieve stable drug level and limited by neutropenia as a serious side effect.http://www.annalspc.com/article.asp?issn=0974-2069;year=2022;volume=15;issue=1;spage=58;epage=60;aulast=Sagiveverolimusrhabdomyomaswolff-parkinson-white |
| spellingShingle | Eyal Sagiv Sathish Mallenahalli Chikkabyrappa Jeffrey Conwell Mark Lewin Terrence Un Hoong Chun Use of Everolimus to treat cardiac rhabdomyomas and incessant arrhythmias in a newborn: Benefits and complications Annals of Pediatric Cardiology everolimus rhabdomyomas wolff-parkinson-white |
| title | Use of Everolimus to treat cardiac rhabdomyomas and incessant arrhythmias in a newborn: Benefits and complications |
| title_full | Use of Everolimus to treat cardiac rhabdomyomas and incessant arrhythmias in a newborn: Benefits and complications |
| title_fullStr | Use of Everolimus to treat cardiac rhabdomyomas and incessant arrhythmias in a newborn: Benefits and complications |
| title_full_unstemmed | Use of Everolimus to treat cardiac rhabdomyomas and incessant arrhythmias in a newborn: Benefits and complications |
| title_short | Use of Everolimus to treat cardiac rhabdomyomas and incessant arrhythmias in a newborn: Benefits and complications |
| title_sort | use of everolimus to treat cardiac rhabdomyomas and incessant arrhythmias in a newborn benefits and complications |
| topic | everolimus rhabdomyomas wolff-parkinson-white |
| url | http://www.annalspc.com/article.asp?issn=0974-2069;year=2022;volume=15;issue=1;spage=58;epage=60;aulast=Sagiv |
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