NOX2-Induced High Glycolytic Activity Contributes to the Gain of COL5A1-Mediated Mesenchymal Phenotype in GBM

NOX2-Induced High Glycolytic Activity Contributes to the Gain of COL5A1-Mediated Mesenchymal Phenotype in GBM

The alteration of the cellular metabolism is a hallmark of glioma. The high glycolytic phenotype is a critical factor in the pathogenesis of high-grade glioma, including glioblastoma multiforme (GBM). GBM has been stratified into three subtypes as the proneural, mesenchymal, and classical subtypes....

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Bibliographic Details
Main Authors: Youngjoon Park, Minwoo Park, Junhyung Kim, Juwon Ahn, Jeongmin Sim, Ji-In Bang, Jinhyung Heo, Hyejeong Choi, Kyunggi Cho, Mihye Lee, Jong-Seok Moon, Jaejoon Lim
Format: Article
Language:English
Published: MDPI AG 2022-01-01
Series:Cancers
Subjects:
NOX2
glycolysis
COL5A1
mesenchymal phenotype
GBM
Online Access:https://www.mdpi.com/2072-6694/14/3/516

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