The gut microbiome-metabolome dataset collection: a curated resource for integrative meta-analysis

Abstract Integrative analysis of microbiome and metabolome data obtained from human fecal samples is a promising avenue for better understanding the interplay between bacteria and metabolites in the human gut, in both health and disease. However, acquiring, processing, and unifying such datasets fro...

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Bibliographic Details
Main Authors: Efrat Muller, Yadid M. Algavi, Elhanan Borenstein
Format: Article
Language:English
Published: Nature Portfolio 2022-10-01
Series:npj Biofilms and Microbiomes
Online Access:https://doi.org/10.1038/s41522-022-00345-5
Description
Summary:Abstract Integrative analysis of microbiome and metabolome data obtained from human fecal samples is a promising avenue for better understanding the interplay between bacteria and metabolites in the human gut, in both health and disease. However, acquiring, processing, and unifying such datasets from multiple sources is a daunting and challenging task. Here we present a publicly available, simple-to-use, curated dataset collection of paired fecal microbiome-metabolome data from multiple cohorts. This data resource allows researchers to easily obtain multiple fully processed and integrated microbiome-metabolome datasets, facilitating the discovery of universal microbe-metabolite links, benchmark various microbiome-metabolome integration tools, and compare newly identified microbe-metabolite findings to other published datasets.
ISSN:2055-5008