The LOX-1 receptor ectopically expressed in the liver alleviates atherosclerosis by clearing Ox-LDL from the circulation

The LOX-1 receptor ectopically expressed in the liver alleviates atherosclerosis by clearing Ox-LDL from the circulation

Abstract Objective Oxidized Low-Density-Lipoprotein (Ox-LDL) is the core factor in the development of atherosclerosis. However, there are few therapies aimed at eliminating Ox-LDL. Here in this study, we investigate whether the ectopically expression of the lectin-like oxidized low density lipoprote...

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Bibliographic Details
Main Authors: Zhiwen Wang, Juan Chen, Zhuanglin Zeng, Qing Zhang, Gaohui Du, Xiaopeng Guo, Yumiao Wei
Format: Article
Language:English
Published: BMC 2022-03-01
Series:Molecular Medicine
Subjects:
Ox-LDL
LOX-1
Liver
AAV8
Atherosclerosis
Online Access:https://doi.org/10.1186/s10020-022-00450-3

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