Serum-Induced Proliferation of Human Cardiac Stem Cells Is Modulated via TGFβRI/II and SMAD2/3

Serum-Induced Proliferation of Human Cardiac Stem Cells Is Modulated via TGFβRI/II and SMAD2/3

The ageing phenotype is strongly driven by the exhaustion of adult stem cells (ASCs) and the accumulation of senescent cells. Cardiovascular diseases (CVDs) and heart failure (HF) are strongly linked to the ageing phenotype and are the leading cause of death. As the human heart is considered as an o...

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Bibliographic Details
Main Authors: Kazuko E. Schmidt, Anna L. Höving, Sina Kiani Zahrani, Katerina Trevlopoulou, Barbara Kaltschmidt, Cornelius Knabbe, Christian Kaltschmidt
Format: Article
Language:English
Published: MDPI AG 2024-01-01
Series:International Journal of Molecular Sciences
Subjects:
human cardiac stem cells
human blood serum
proliferation
senescence
ageing
RNA-Seq
Online Access:https://www.mdpi.com/1422-0067/25/2/959

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