Neoatherosclerosis in the stent

Achievements of interventional cardiology in the treatment of coronary artery disease are based on coronary balloon angioplasty with implanting bare metal stents and drug eluting stents. Questions of complications such as early stent thrombosis and restenosis of stent were solved in a considerable d...

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Main Authors: A. A. Komkov, V. P. Mazaev, S. V. Ryazanova
Format: Article
Language:English
Published: Столичная издательская компания 2015-12-01
Series:Рациональная фармакотерапия в кардиологии
Subjects:
Online Access:https://www.rpcardio.online/jour/article/view/443
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author A. A. Komkov
V. P. Mazaev
S. V. Ryazanova
author_facet A. A. Komkov
V. P. Mazaev
S. V. Ryazanova
author_sort A. A. Komkov
collection DOAJ
description Achievements of interventional cardiology in the treatment of coronary artery disease are based on coronary balloon angioplasty with implanting bare metal stents and drug eluting stents. Questions of complications such as early stent thrombosis and restenosis of stent were solved in a considerable degree. However, with the lengthening of the followup period, the problem of late complications became obvious. Except endothelization and fibromuscular proliferation in stented coronary arteries the process of plaque formation has an important influence on later complications in follow-up period more than one year. This process was defined as neoatherosclerosis. This is verified by clinical manifestations of the disease, histological studies, angioscopy, intravascular ultrasound and optical-coherence tomography in stented patients. Dynamic observation of the condition in stentedcoronary arteries showed multistep proliferation with restenosis, its regression, and neoatherosclerosis development. Evidences of neoatherosclerosis formation in stented coronary arteries are considered in this review.
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spelling doaj.art-523d15e8992d4ab6bf9be84be5c5eb5e2024-04-01T07:43:25ZengСтоличная издательская компанияРациональная фармакотерапия в кардиологии1819-64462225-36532015-12-0111662663310.20996/1819-6446-2015-11-6-626-633443Neoatherosclerosis in the stentA. A. Komkov0V. P. Mazaev1S. V. Ryazanova2State Research Centre for Preventive Medicine. Petroverigsky per. 10, Moscow, 101990 RussiaState Research Centre for Preventive Medicine. Petroverigsky per. 10, Moscow, 101990 RussiaState Research Centre for Preventive Medicine. Petroverigsky per. 10, Moscow, 101990 RussiaAchievements of interventional cardiology in the treatment of coronary artery disease are based on coronary balloon angioplasty with implanting bare metal stents and drug eluting stents. Questions of complications such as early stent thrombosis and restenosis of stent were solved in a considerable degree. However, with the lengthening of the followup period, the problem of late complications became obvious. Except endothelization and fibromuscular proliferation in stented coronary arteries the process of plaque formation has an important influence on later complications in follow-up period more than one year. This process was defined as neoatherosclerosis. This is verified by clinical manifestations of the disease, histological studies, angioscopy, intravascular ultrasound and optical-coherence tomography in stented patients. Dynamic observation of the condition in stentedcoronary arteries showed multistep proliferation with restenosis, its regression, and neoatherosclerosis development. Evidences of neoatherosclerosis formation in stented coronary arteries are considered in this review.https://www.rpcardio.online/jour/article/view/443neoatherosclerosislate catch-uplate stent thrombosisrestenosis complications
spellingShingle A. A. Komkov
V. P. Mazaev
S. V. Ryazanova
Neoatherosclerosis in the stent
Рациональная фармакотерапия в кардиологии
neoatherosclerosis
late catch-up
late stent thrombosis
restenosis complications
title Neoatherosclerosis in the stent
title_full Neoatherosclerosis in the stent
title_fullStr Neoatherosclerosis in the stent
title_full_unstemmed Neoatherosclerosis in the stent
title_short Neoatherosclerosis in the stent
title_sort neoatherosclerosis in the stent
topic neoatherosclerosis
late catch-up
late stent thrombosis
restenosis complications
url https://www.rpcardio.online/jour/article/view/443
work_keys_str_mv AT aakomkov neoatherosclerosisinthestent
AT vpmazaev neoatherosclerosisinthestent
AT svryazanova neoatherosclerosisinthestent