Association between anxiety and metabolic syndrome: An updated systematic review and meta-analysis
ObjectivePrevious studies have demonstrated an association between anxiety and metabolic syndrome (MetS). However, the association is still controversial. This updated meta-analysis aimed to reanalyze the association between anxiety and MetS.MethodsWe comprehensively searched PubMed, Embase and Web...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2023-02-01
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| Series: | Frontiers in Psychiatry |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fpsyt.2023.1118836/full |
| _version_ | 1797905116204892160 |
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| author | Shuang Ji Yujiao Chen Yuying Zhou Yiting Cao Xiao Li Xiao Li Guoyong Ding Fang Tang Fang Tang Fang Tang |
| author_facet | Shuang Ji Yujiao Chen Yuying Zhou Yiting Cao Xiao Li Xiao Li Guoyong Ding Fang Tang Fang Tang Fang Tang |
| author_sort | Shuang Ji |
| collection | DOAJ |
| description | ObjectivePrevious studies have demonstrated an association between anxiety and metabolic syndrome (MetS). However, the association is still controversial. This updated meta-analysis aimed to reanalyze the association between anxiety and MetS.MethodsWe comprehensively searched PubMed, Embase and Web of Science for all related studies published before January 23, 2023. Observational studies that informed effect size with 95% confidence interval (CI) for the association between anxiety and MetS were included. According to heterogeneity between studies, fixed or random effects models were applied to calculate the pooled effect size. Publication bias was examined by funnel plots.ResultsThe research included 24 cross-sectional studies: 20 studies used MetS as the dependent variable with a pooled OR of 1.07 (95% CI: 1.01–1.13) and four studies used anxiety as the dependent variable with a pooled OR of 1.14 (95% CI: 1.07–1.23). Three cohort studies were found: two studies detected the association of baseline anxiety with the risk of MetS, one of the studies demonstrated a significant association, but a similar result was not found in another study; one study showed no significant association between baseline MetS and the risk of anxiety.ConclusionCross-sectional studies indicated an association between anxiety and MetS. The results from cohort studies are still inconsistent and limited. More large-scale prospective studies are needed to further reveal the causal relationship of anxiety with MetS. |
| first_indexed | 2024-04-10T09:59:55Z |
| format | Article |
| id | doaj.art-52411ce7edaa418c99af5f5fb8331ffb |
| institution | Directory Open Access Journal |
| issn | 1664-0640 |
| language | English |
| last_indexed | 2024-04-10T09:59:55Z |
| publishDate | 2023-02-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Psychiatry |
| spelling | doaj.art-52411ce7edaa418c99af5f5fb8331ffb2023-02-16T09:58:50ZengFrontiers Media S.A.Frontiers in Psychiatry1664-06402023-02-011410.3389/fpsyt.2023.11188361118836Association between anxiety and metabolic syndrome: An updated systematic review and meta-analysisShuang Ji0Yujiao Chen1Yuying Zhou2Yiting Cao3Xiao Li4Xiao Li5Guoyong Ding6Fang Tang7Fang Tang8Fang Tang9Department of Neurology, Shandong Provincial Qianfoshan Hospital, Weifang Medical University and Shandong Institute of Neuroimmunology, Jinan, ChinaDepartment of Neurology, Shandong Provincial Qianfoshan Hospital, Weifang Medical University and Shandong Institute of Neuroimmunology, Jinan, ChinaDepartment of Neurology, Shandong Provincial Qianfoshan Hospital, Weifang Medical University and Shandong Institute of Neuroimmunology, Jinan, ChinaDepartment of Neurology, Shandong Provincial Qianfoshan Hospital, Weifang Medical University and Shandong Institute of Neuroimmunology, Jinan, ChinaDepartment of Clinical Pharmacy, The First Affiliated Hospital of Shandong First Medical University & Shandong Provincial Qianfoshan Hospital, Jinan, ChinaDepartment of Clinical Pharmacy, Shandong Provincial Qianfoshan Hospital, Shandong University, Jinan, ChinaSchool of Public Health, Shandong First Medical University & Shandong Academy of Medical Sciences, Jinan, ChinaDepartment of Neurology, Shandong Provincial Qianfoshan Hospital, Weifang Medical University and Shandong Institute of Neuroimmunology, Jinan, ChinaCenter for Big Data Research in Health and Medicine, The First Affiliated Hospital of Shandong First Medical University, Jinan, ChinaShandong Provincial Qianfoshan Hospital, Cheeloo College of Medicine, Shandong University, Jinan, ChinaObjectivePrevious studies have demonstrated an association between anxiety and metabolic syndrome (MetS). However, the association is still controversial. This updated meta-analysis aimed to reanalyze the association between anxiety and MetS.MethodsWe comprehensively searched PubMed, Embase and Web of Science for all related studies published before January 23, 2023. Observational studies that informed effect size with 95% confidence interval (CI) for the association between anxiety and MetS were included. According to heterogeneity between studies, fixed or random effects models were applied to calculate the pooled effect size. Publication bias was examined by funnel plots.ResultsThe research included 24 cross-sectional studies: 20 studies used MetS as the dependent variable with a pooled OR of 1.07 (95% CI: 1.01–1.13) and four studies used anxiety as the dependent variable with a pooled OR of 1.14 (95% CI: 1.07–1.23). Three cohort studies were found: two studies detected the association of baseline anxiety with the risk of MetS, one of the studies demonstrated a significant association, but a similar result was not found in another study; one study showed no significant association between baseline MetS and the risk of anxiety.ConclusionCross-sectional studies indicated an association between anxiety and MetS. The results from cohort studies are still inconsistent and limited. More large-scale prospective studies are needed to further reveal the causal relationship of anxiety with MetS.https://www.frontiersin.org/articles/10.3389/fpsyt.2023.1118836/fullanxietymetabolic syndromecross-sectional studycohort studymeta-analysis |
| spellingShingle | Shuang Ji Yujiao Chen Yuying Zhou Yiting Cao Xiao Li Xiao Li Guoyong Ding Fang Tang Fang Tang Fang Tang Association between anxiety and metabolic syndrome: An updated systematic review and meta-analysis Frontiers in Psychiatry anxiety metabolic syndrome cross-sectional study cohort study meta-analysis |
| title | Association between anxiety and metabolic syndrome: An updated systematic review and meta-analysis |
| title_full | Association between anxiety and metabolic syndrome: An updated systematic review and meta-analysis |
| title_fullStr | Association between anxiety and metabolic syndrome: An updated systematic review and meta-analysis |
| title_full_unstemmed | Association between anxiety and metabolic syndrome: An updated systematic review and meta-analysis |
| title_short | Association between anxiety and metabolic syndrome: An updated systematic review and meta-analysis |
| title_sort | association between anxiety and metabolic syndrome an updated systematic review and meta analysis |
| topic | anxiety metabolic syndrome cross-sectional study cohort study meta-analysis |
| url | https://www.frontiersin.org/articles/10.3389/fpsyt.2023.1118836/full |
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