Probing the Binding Requirements of Modified Nucleosides with the DNA Nuclease SNM1A

Probing the Binding Requirements of Modified Nucleosides with the DNA Nuclease SNM1A

SNM1A is a nuclease that is implicated in DNA interstrand crosslink repair and, as such, its inhibition is of interest for overcoming resistance to chemotherapeutic crosslinking agents. However, the number and identity of the metal ion(s) in the active site of SNM1A are still unconfirmed, and only a...

Detaylı Bibliyografya
Asıl Yazarlar:	Eva-Maria Dürr, Joanna F. McGouran
Materyal Türü:	Makale
Dil:	English
Baskı/Yayın Bilgisi:	MDPI AG 2021-01-01
Seri Bilgileri:	Molecules
Konular:	nuclease interstrand crosslink repair SNM1A nucleoside inhibitor malonate hydroxamic acid
Online Erişim:	https://www.mdpi.com/1420-3049/26/2/320

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