Arctigenin: pharmacology, total synthesis, and progress in structure modification
Arctium lappa L. is a prevalent medicinal herb and a health supplement that is commonly used in Asia. Over the last few decades, the bioactive component arctigenin has attracted the attention of researchers because of its anti-inflammatory, antioxidant, immunomodulatory, multiple sclerosis fighting,...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Taylor & Francis Group
2022-12-01
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| Series: | Journal of Enzyme Inhibition and Medicinal Chemistry |
| Subjects: | |
| Online Access: | https://www.tandfonline.com/doi/10.1080/14756366.2022.2115035 |
| _version_ | 1811209672328216576 |
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| author | Dan Wu Lili Jin Xing Huang Hao Deng Qing-kun Shen Zhe-shan Quan Changhao Zhang Hong-Yan Guo |
| author_facet | Dan Wu Lili Jin Xing Huang Hao Deng Qing-kun Shen Zhe-shan Quan Changhao Zhang Hong-Yan Guo |
| author_sort | Dan Wu |
| collection | DOAJ |
| description | Arctium lappa L. is a prevalent medicinal herb and a health supplement that is commonly used in Asia. Over the last few decades, the bioactive component arctigenin has attracted the attention of researchers because of its anti-inflammatory, antioxidant, immunomodulatory, multiple sclerosis fighting, antitumor, and anti-leukemia properties. After summarising the research and literature on arctigenin, this study outlines the current status of research on pharmacological activity, total synthesis, and structural modification of arctigenin. The purpose of this study is to assist academics in obtaining a more comprehensive understanding of the research progress on arctigenin and to provide constructive suggestions for further investigation of this useful molecule. |
| first_indexed | 2024-04-12T04:43:12Z |
| format | Article |
| id | doaj.art-5241fc5b81fb4594b8ab197dcb7f552c |
| institution | Directory Open Access Journal |
| issn | 1475-6366 1475-6374 |
| language | English |
| last_indexed | 2024-04-12T04:43:12Z |
| publishDate | 2022-12-01 |
| publisher | Taylor & Francis Group |
| record_format | Article |
| series | Journal of Enzyme Inhibition and Medicinal Chemistry |
| spelling | doaj.art-5241fc5b81fb4594b8ab197dcb7f552c2022-12-22T03:47:33ZengTaylor & Francis GroupJournal of Enzyme Inhibition and Medicinal Chemistry1475-63661475-63742022-12-013712452247710.1080/14756366.2022.2115035Arctigenin: pharmacology, total synthesis, and progress in structure modificationDan Wu0Lili Jin1Xing Huang2Hao Deng3Qing-kun Shen4Zhe-shan Quan5Changhao Zhang6Hong-Yan Guo7Key Laboratory of Natural Medicines of the Changbai Mountain, Affifiliated Ministry of Education, College of Pharmacy, Yanbian University, Jilin, ChinaKey Laboratory of Natural Medicines of the Changbai Mountain, Affifiliated Ministry of Education, College of Pharmacy, Yanbian University, Jilin, ChinaKey Laboratory of Natural Medicines of the Changbai Mountain, Affifiliated Ministry of Education, College of Pharmacy, Yanbian University, Jilin, ChinaKey Laboratory of Natural Medicines of the Changbai Mountain, Affifiliated Ministry of Education, College of Pharmacy, Yanbian University, Jilin, ChinaKey Laboratory of Natural Medicines of the Changbai Mountain, Affifiliated Ministry of Education, College of Pharmacy, Yanbian University, Jilin, ChinaKey Laboratory of Natural Medicines of the Changbai Mountain, Affifiliated Ministry of Education, College of Pharmacy, Yanbian University, Jilin, ChinaKey Laboratory of Natural Medicines of the Changbai Mountain, Affifiliated Ministry of Education, College of Pharmacy, Yanbian University, Jilin, ChinaKey Laboratory of Natural Medicines of the Changbai Mountain, Affifiliated Ministry of Education, College of Pharmacy, Yanbian University, Jilin, ChinaArctium lappa L. is a prevalent medicinal herb and a health supplement that is commonly used in Asia. Over the last few decades, the bioactive component arctigenin has attracted the attention of researchers because of its anti-inflammatory, antioxidant, immunomodulatory, multiple sclerosis fighting, antitumor, and anti-leukemia properties. After summarising the research and literature on arctigenin, this study outlines the current status of research on pharmacological activity, total synthesis, and structural modification of arctigenin. The purpose of this study is to assist academics in obtaining a more comprehensive understanding of the research progress on arctigenin and to provide constructive suggestions for further investigation of this useful molecule.https://www.tandfonline.com/doi/10.1080/14756366.2022.2115035Arctigeninpharmacologytotal synthesisstructure modification |
| spellingShingle | Dan Wu Lili Jin Xing Huang Hao Deng Qing-kun Shen Zhe-shan Quan Changhao Zhang Hong-Yan Guo Arctigenin: pharmacology, total synthesis, and progress in structure modification Journal of Enzyme Inhibition and Medicinal Chemistry Arctigenin pharmacology total synthesis structure modification |
| title | Arctigenin: pharmacology, total synthesis, and progress in structure modification |
| title_full | Arctigenin: pharmacology, total synthesis, and progress in structure modification |
| title_fullStr | Arctigenin: pharmacology, total synthesis, and progress in structure modification |
| title_full_unstemmed | Arctigenin: pharmacology, total synthesis, and progress in structure modification |
| title_short | Arctigenin: pharmacology, total synthesis, and progress in structure modification |
| title_sort | arctigenin pharmacology total synthesis and progress in structure modification |
| topic | Arctigenin pharmacology total synthesis structure modification |
| url | https://www.tandfonline.com/doi/10.1080/14756366.2022.2115035 |
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