Isopropyl Myristate-Modified Polyether-Urethane Coatings as Protective Barriers for Implantable Medical Devices
Polyurethane films have potential applications in medicine, especially for packaging implantable medical devices. Although polyether-urethanes have superior mechanical properties and are biocompatible, achieving water resistance is still a challenge. Polyether based polyurethanes with two different...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2009-06-01
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| Series: | Materials |
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| Online Access: | http://www.mdpi.com/1996-1944/2/3/719/ |
| _version_ | 1811299091882180608 |
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| author | Pankaj Vadgama Ihtesham U. Rehman Deepen Paul Alireza Moshaverinia Jaroslaw M. Wasikiewicz Nima Roohpour |
| author_facet | Pankaj Vadgama Ihtesham U. Rehman Deepen Paul Alireza Moshaverinia Jaroslaw M. Wasikiewicz Nima Roohpour |
| author_sort | Pankaj Vadgama |
| collection | DOAJ |
| description | Polyurethane films have potential applications in medicine, especially for packaging implantable medical devices. Although polyether-urethanes have superior mechanical properties and are biocompatible, achieving water resistance is still a challenge. Polyether based polyurethanes with two different molecular weights (PTMO1000, PTMO2000) were prepared from 4,4’-diphenylmethane diisocyanate and poly(tetra-methylene oxide). Polymer films were introduced using different concentrations (0.5-10 wt %) of isopropyl myristate lipid (IPM) as a non-toxic modifying agent. The physical and mechanical properties of these polymers were characterised using physical and spectroscopy techniques (FTIR, Raman, DSC, DMA, tensile testing). Water contact angle and water uptake of the membranes as a function of IPM concentration was also determined accordingly. The FTIR and Raman data indicate that IPM is dispersed in polyurethane at ≤ 2wt% and thermal analysis confirmed this miscibility to be dependent on soft segment length. Modified polymers showed increased tensile strength and failure strain as well as reduced water uptake by up to 24% at 1-2 wt% IPM. |
| first_indexed | 2024-04-13T06:30:53Z |
| format | Article |
| id | doaj.art-5243afed260e4f7d88614abecc67abe8 |
| institution | Directory Open Access Journal |
| issn | 1996-1944 |
| language | English |
| last_indexed | 2024-04-13T06:30:53Z |
| publishDate | 2009-06-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Materials |
| spelling | doaj.art-5243afed260e4f7d88614abecc67abe82022-12-22T02:58:10ZengMDPI AGMaterials1996-19442009-06-012371973310.3390/ma2030719Isopropyl Myristate-Modified Polyether-Urethane Coatings as Protective Barriers for Implantable Medical DevicesPankaj VadgamaIhtesham U. RehmanDeepen PaulAlireza MoshaveriniaJaroslaw M. WasikiewiczNima RoohpourPolyurethane films have potential applications in medicine, especially for packaging implantable medical devices. Although polyether-urethanes have superior mechanical properties and are biocompatible, achieving water resistance is still a challenge. Polyether based polyurethanes with two different molecular weights (PTMO1000, PTMO2000) were prepared from 4,4’-diphenylmethane diisocyanate and poly(tetra-methylene oxide). Polymer films were introduced using different concentrations (0.5-10 wt %) of isopropyl myristate lipid (IPM) as a non-toxic modifying agent. The physical and mechanical properties of these polymers were characterised using physical and spectroscopy techniques (FTIR, Raman, DSC, DMA, tensile testing). Water contact angle and water uptake of the membranes as a function of IPM concentration was also determined accordingly. The FTIR and Raman data indicate that IPM is dispersed in polyurethane at ≤ 2wt% and thermal analysis confirmed this miscibility to be dependent on soft segment length. Modified polymers showed increased tensile strength and failure strain as well as reduced water uptake by up to 24% at 1-2 wt% IPM.http://www.mdpi.com/1996-1944/2/3/719/polyether-urethaneisopropyl myristateblendphysical properties |
| spellingShingle | Pankaj Vadgama Ihtesham U. Rehman Deepen Paul Alireza Moshaverinia Jaroslaw M. Wasikiewicz Nima Roohpour Isopropyl Myristate-Modified Polyether-Urethane Coatings as Protective Barriers for Implantable Medical Devices Materials polyether-urethane isopropyl myristate blend physical properties |
| title | Isopropyl Myristate-Modified Polyether-Urethane Coatings as Protective Barriers for Implantable Medical Devices |
| title_full | Isopropyl Myristate-Modified Polyether-Urethane Coatings as Protective Barriers for Implantable Medical Devices |
| title_fullStr | Isopropyl Myristate-Modified Polyether-Urethane Coatings as Protective Barriers for Implantable Medical Devices |
| title_full_unstemmed | Isopropyl Myristate-Modified Polyether-Urethane Coatings as Protective Barriers for Implantable Medical Devices |
| title_short | Isopropyl Myristate-Modified Polyether-Urethane Coatings as Protective Barriers for Implantable Medical Devices |
| title_sort | isopropyl myristate modified polyether urethane coatings as protective barriers for implantable medical devices |
| topic | polyether-urethane isopropyl myristate blend physical properties |
| url | http://www.mdpi.com/1996-1944/2/3/719/ |
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