Morphometrical, Morphological, and Immunocytochemical Characterization of a Tool for Cytotoxicity Research: 3D Cultures of Breast Cell Lines Grown in Ultra-Low Attachment Plates

Three-dimensional cell cultures may better mimic avascular tumors. Yet, they still lack characterization and standardization. Therefore, this study aimed to (a) generate multicellular aggregates (MCAs) of four breast cell lines: MCF7, MDA-MB-231, and SKBR3 (tumoral) and MCF12A (non-tumoral) using ul...

Full description

Bibliographic Details
Main Authors: Fernanda Malhão, Ana Catarina Macedo, Alice Abreu Ramos, Eduardo Rocha
Format: Article
Language:English
Published: MDPI AG 2022-07-01
Series:Toxics
Subjects:
Online Access:https://www.mdpi.com/2305-6304/10/8/415