Levetiracetam enhances the temozolomide effect on glioblastoma stem cell proliferation and apoptosis

Levetiracetam enhances the temozolomide effect on glioblastoma stem cell proliferation and apoptosis

Abstract Background Glioblastoma multiforme (GBM) is a highly aggressive brain tumor in which cancer cells with stem cell-like features, called cancer stem cells (CSCs), were identified. Two CSC populations have been previously identified in GBM, one derived from the GBM area called enhanced lesion...

Full description

Bibliographic Details
Main Authors: Bianca Maria Scicchitano, Silvia Sorrentino, Gabriella Proietti, Gina Lama, Gabriella Dobrowolny, Angela Catizone, Elena Binda, Luigi Maria Larocca, Gigliola Sica
Format: Article
Language:English
Published: BMC 2018-09-01
Series:Cancer Cell International
Subjects:
Glioblastoma
Cancer stem cells
MGMT
Temozolomide
Levetiracetam
Online Access:http://link.springer.com/article/10.1186/s12935-018-0626-8

Similar Items

Similar Items