Dexmedetomidine overdosage: An unusual presentation
We present a case of dexmedetomidine toxicity in a 3-year-old child. The case report describes the features and outlines the treatment strategy adopted. The child presented with bradypnoea, bradycardia, hypotension, deep hypnosis and miosis. He was successfully managed with oxygen, saline boluses an...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wolters Kluwer Medknow Publications
2013-01-01
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| Series: | Indian Journal of Anaesthesia |
| Subjects: | |
| Online Access: | http://www.ijaweb.org/article.asp?issn=0019-5049;year=2013;volume=57;issue=3;spage=289;epage=291;aulast=Nath |
| _version_ | 1828869565305585664 |
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| author | Soumya S Nath Sujan Singh Sundeep T Pawar |
| author_facet | Soumya S Nath Sujan Singh Sundeep T Pawar |
| author_sort | Soumya S Nath |
| collection | DOAJ |
| description | We present a case of dexmedetomidine toxicity in a 3-year-old child. The case report describes the features and outlines the treatment strategy adopted. The child presented with bradypnoea, bradycardia, hypotension, deep hypnosis and miosis. He was successfully managed with oxygen, saline boluses and adrenaline infusion. He became haemodynamically stable with adrenaline infusion. He started responding to painful stimuli in 3 h and became oriented in 7 h. Dexmedetomidine, a selective α2 adrenoceptor agonist, is claimed to have a wide safety margin. This case report highlights the fact that dexmedetomidine administered in a toxic dose may be life-threatening may present with miosis and adrenaline infusion may be a useful supportive treatment. |
| first_indexed | 2024-12-13T05:52:47Z |
| format | Article |
| id | doaj.art-524ae6a742b647c884ff92f0b9ef10c8 |
| institution | Directory Open Access Journal |
| issn | 0019-5049 |
| language | English |
| last_indexed | 2024-12-13T05:52:47Z |
| publishDate | 2013-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Indian Journal of Anaesthesia |
| spelling | doaj.art-524ae6a742b647c884ff92f0b9ef10c82022-12-21T23:57:30ZengWolters Kluwer Medknow PublicationsIndian Journal of Anaesthesia0019-50492013-01-0157328929110.4103/0019-5049.115617Dexmedetomidine overdosage: An unusual presentationSoumya S NathSujan SinghSundeep T PawarWe present a case of dexmedetomidine toxicity in a 3-year-old child. The case report describes the features and outlines the treatment strategy adopted. The child presented with bradypnoea, bradycardia, hypotension, deep hypnosis and miosis. He was successfully managed with oxygen, saline boluses and adrenaline infusion. He became haemodynamically stable with adrenaline infusion. He started responding to painful stimuli in 3 h and became oriented in 7 h. Dexmedetomidine, a selective α2 adrenoceptor agonist, is claimed to have a wide safety margin. This case report highlights the fact that dexmedetomidine administered in a toxic dose may be life-threatening may present with miosis and adrenaline infusion may be a useful supportive treatment.http://www.ijaweb.org/article.asp?issn=0019-5049;year=2013;volume=57;issue=3;spage=289;epage=291;aulast=NathDexmedetomidinemiosisoverdose |
| spellingShingle | Soumya S Nath Sujan Singh Sundeep T Pawar Dexmedetomidine overdosage: An unusual presentation Indian Journal of Anaesthesia Dexmedetomidine miosis overdose |
| title | Dexmedetomidine overdosage: An unusual presentation |
| title_full | Dexmedetomidine overdosage: An unusual presentation |
| title_fullStr | Dexmedetomidine overdosage: An unusual presentation |
| title_full_unstemmed | Dexmedetomidine overdosage: An unusual presentation |
| title_short | Dexmedetomidine overdosage: An unusual presentation |
| title_sort | dexmedetomidine overdosage an unusual presentation |
| topic | Dexmedetomidine miosis overdose |
| url | http://www.ijaweb.org/article.asp?issn=0019-5049;year=2013;volume=57;issue=3;spage=289;epage=291;aulast=Nath |
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