β-Hydroxybutyrate as an epigenetic modifier: Underlying mechanisms and implications

β-Hydroxybutyrate as an epigenetic modifier: Underlying mechanisms and implications

Previous studies have found that β-Hydroxybutyrate (BHB), the main component of ketone bodies, is of physiological importance as a backup energy source during starvation or induces diabetic ketoacidosis when insulin deficiency occurs. Ketogenic diets (KD) have been used as metabolic therapy for over...

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Bibliographic Details
Main Authors: Yanqiu He, Xi Cheng, Tingting Zhou, Dongze Li, Juan Peng, Yong Xu, Wei Huang
Format: Article
Language:English
Published: Elsevier 2023-11-01
Series:Heliyon
Subjects:
β-hydroxybutyrate
Epigenetics
Histone post-translational modification
Ketogenic diet
DNA methylation
microRNAs
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844023083068

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