Dose-response association of metformin use and risk of age-related macular degeneration among patients with type 2 diabetes mellitus: a population-based study

Dose-response association of metformin use and risk of age-related macular degeneration among patients with type 2 diabetes mellitus: a population-based study

Background: Recent studies have demonstrated that patients with type 2 diabetes mellitus (T2DM) who receive metformin have a decreased risk of developing age-related macular degeneration (AMD). However, other studies have also suggested that metformin may increase the risk of AMD development. Theref...

Full description

Bibliographic Details
Main Authors:	Kuang-Hua Huang, Ya-Lan Chang, Chiachi Bonnie Lee, Shuo-Yan Gau, Tung-Han Tsai, Ning-Jen Chung, Chien-Ying Lee
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2023-11-01
Series:	Frontiers in Pharmacology
Subjects:	age-related macular degeneration metformin type 2 diabetes mellitus Pharmacoepidemiology real world evidence (RWE)
Online Access:	https://www.frontiersin.org/articles/10.3389/fphar.2023.1275095/full

Similar Items

The Risk of Age-Related Macular Degeneration Is Reduced in Type 2 Diabetes Patients Who Use Metformin
by: Chin-Hsiao Tseng
Published: (2023-02-01)

Newly-found functions of metformin for the prevention and treatment of age-related macular degeneration
by: Kuan-Rong Dang, et al.
Published: (2021-08-01)

The Correlation between Metformin Use and Incident Dementia in Patients with New-Onset Diabetes Mellitus: A Population-Based Study
by: Kuang-Hua Huang, et al.
Published: (2023-04-01)

Dose–Response Association of Metformin with Parkinson’s Disease Odds in Type 2 Diabetes Mellitus
by: Kuang-Hua Huang, et al.
Published: (2022-04-01)

Editorial: Real-World Evidence of Pediatric Exposure to Psychopharmacologic Medications
by: Julie M. Zito, et al.
Published: (2022-06-01)

What do Cochrane systematic reviews say about interventions for age-related macular degeneration?
by: Vania Mozetic, et al.
Published: (2020-03-01)

Absence of an Association between Macular Degeneration and Young-Onset Dementia
by: Tung-Mei Tammy Kuang, et al.
Published: (2022-02-01)

Real-world evidence (RWE): A challenge for regulatory agencies discussion of the RWE conference with the network of the european medicine agencies, patients, and experts
by: Patrick Maison, et al.
Published: (2022-07-01)

The Relationship between Dietary Calcium and Age-Related Macular Degeneration
by: Yuan-Yuei Chen, et al.
Published: (2023-01-01)

Neuroprotection for Age-Related Macular Degeneration
by: Jonathan B. Lin, MD, PhD, et al.
Published: (2022-12-01)

Comparison of efficacy between Ranibizumab and Conbercept for wet age-related macular degeneration
by: Qiang Fan, et al.
Published: (2018-08-01)

Management of Cataract in Patients with Age-Related Macular Degeneration
by: Hemal Mehta
Published: (2021-06-01)

METformin for the MINimization of Geographic Atrophy Progression (METforMIN): A Randomized Trial
by: Liangbo Linus Shen, MD, et al.
Published: (2024-05-01)

Acquired Vitelliform Macular Degeneration: Characteristics and Challenges of Managing Subretinal Fluid
by: Joseph Juliano, et al.
Published: (2021-10-01)

Risk of antidepressant initiation among users of cardiovascular agents and metformin.
by: Ivana Bojanić, et al.
Published: (2023-04-01)

Epidemiology of Diagnosed Age-related Macular Degeneration in Germany: An Evaluation of the Prevalence Using AOK PLUS Claims Data
by: Alexander K. Schuster, et al.
Published: (2024-02-01)

Association of Age-Related Macular Degeneration with Prior Hyperthyroidism and Hypothyroidism: A Case–Control Study
by: Shih-Han Hung, et al.
Published: (2022-04-01)

Roles and mechanisms of long non-coding RNAs in age-related macular degeneration
by: Rong Zhang, et al.
Published: (2023-11-01)

Smoking,serum antioxidant vitamin levels and age-related macular degeneration
by: Sezen Akkaya Çakir, et al.
Published: (2014-05-01)

Possible Association of Periodontal Disease and Macular Degeneration: A Case-Control Study
by: Federica Di Spirito, et al.
Published: (2020-12-01)

Biomarkers of macular neovascularisation activity using optical coherence tomography angiography in treated stable neovascular age related macular degeneration
by: Daren Hanumunthadu, et al.
Published: (2023-02-01)

NORMAL FLUENCE PHOTODYNAMIC THERAPY ASSOCIATED WITH LAMELLAR MACULAR HOLES IN EXUDATIVE AGE RELATED MACULAR DEGENERATION
by: Alvaro Rodriguez, et al.
Published: (2014-09-01)

Beyond the Complement Cascade: Insights into Systemic Immunosenescence and Inflammaging in Age-Related Macular Degeneration and Current Barriers to Treatment
by: Adnan H. Khan, et al.
Published: (2023-06-01)

Implantation of the First IMT Macular Lens in Age-Related Macular Degeneration (Literature Review)
by: M. M. Bikbov, et al.
Published: (2019-08-01)

Characterizing Macular Neovascularization in Myopic Macular Degeneration and Age-Related Macular Degeneration Using Swept Source OCTA
by: Sayah DN, et al.
Published: (2023-12-01)

Dry age-related macular degeneration - therapeutic possibilities and research directions
by: Alicja Zajdel
Published: (2022-10-01)

Evaluation of serum interferons in patients with age-related macular degeneration
by: Mehrdad Afarid, et al.
Published: (2019-01-01)

Full-thickness macular hole formation following anti-VEGF injections for neovascular age-related macular degeneration
by: Kabanarou SA, et al.
Published: (2017-05-01)

Prevalence and genetic analyses of selected age-related macular degeneration-related polymorphisms and their responses to intravitreal ranibizumab
by: Mohamad, Nur Afiqah
Published: (2018)

HBV infection increases the risk of macular degeneration: the roles of HBx-mediated sensitization of retinal pigment epithelial cells to UV and blue light irradiation
by: Ruey-Hwang Chou, et al.
Published: (2018-08-01)

Metformin and risk of gingival/periodontal diseases in diabetes patients: A retrospective cohort study
by: Chin-Hsiao Tseng, et al.
Published: (2022-10-01)

Intravitreal aflibercept in neovascular age-related macular degeneration previously treated with ranibizumab
by: Rachel Hui Fen Lim, et al.
Published: (2017-03-01)

Insights into the nutritional prevention of macular degeneration based on a comparative topic modeling approach
by: Lucas Jacaruso
Published: (2024-03-01)

Molecular Mechanisms of Retinal Pigment Epithelium Dysfunction in Age-Related Macular Degeneration
by: Jongmin Kim, et al.
Published: (2021-11-01)

Diurnal variation of optical coherence tomography–based macular fluid in exudative age-related macular degeneration
by: Blake H. Fortes, et al.
Published: (2023-09-01)

Prescription trend and lactic acidosis in patients prescribed metformin before and after the revision of package insert for allowing metformin administration to patients with moderately decreased kidney function based on real-world data from MID-NET® in Japan
by: Takashi Waki, et al.
Published: (2024-01-01)

Changes of retinal structure in macular region after treatment with Conbercept for wet age-related macular degeneration
by: Ping-Ping Liu, et al.
Published: (2020-02-01)

Macular and Plasma Xanthophylls Are Higher in Age-related Macular Degeneration than in Normal Aging
by: Gerald McGwin, Jr., PhD, et al.
Published: (2023-06-01)

Effect of intravitreal Conbercept on wet age-related macular degeneration and polypoidal choroidal vasculopathy
by: Ying-Chun Li, et al.
Published: (2015-11-01)

Prevention of the Onset of Age-Related Macular Degeneration
by: Emiliano Di Carlo, et al.
Published: (2021-07-01)