The Cytotoxicity of the Ajoene Analogue BisPMB in WHCO1 Oesophageal Cancer Cells Is Mediated by CHOP/GADD153

The Cytotoxicity of the Ajoene Analogue BisPMB in WHCO1 Oesophageal Cancer Cells Is Mediated by CHOP/GADD153

Garlic is a food and medicinal plant that has been used in folk medicine since ancient times for its beneficial health effects, which include protection against cancer. Crushed garlic cloves contain an array of small sulfur-rich compounds such as ajoene. Ajoene is able to interfere with biological p...

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Bibliographic Details
Main Authors: Vuyolwethu Siyo, Georgia Schäfer, Roger Hunter, Andriy Grafov, Iryna Grafova, Martin Nieger, Arieh A. Katz, M. Iqbal Parker, Catherine H. Kaschula
Format: Article
Language:English
Published: MDPI AG 2017-05-01
Series:Molecules
Subjects:
ajoene
garlic
cancer prevention
ER stress
unfolded protein response
CHOP/GADD153
Online Access:http://www.mdpi.com/1420-3049/22/6/892

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