PCSK9 inhibitor alleviates experimental pulmonary fibrosis-induced pulmonary hypertension via attenuating epithelial-mesenchymal transition by suppressing Wnt/β-catenin signaling in vivo and in vitro
BackgroundThe co-occurrence of pulmonary hypertension (PH) in patients with pulmonary fibrosis (PF) is linked to a more unfavorable prognosis and increased mortality compared to PF cases without PH. Early intervention and comprehensive management are pivotal for improving survival outcomes. Proprote...
প্রধান লেখক: | , , , , , , |
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বিন্যাস: | প্রবন্ধ |
ভাষা: | English |
প্রকাশিত: |
Frontiers Media S.A.
2024-12-01
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মালা: | Frontiers in Medicine |
বিষয়গুলি: | |
অনলাইন ব্যবহার করুন: | https://www.frontiersin.org/articles/10.3389/fmed.2024.1509168/full |