PCSK9 inhibitor alleviates experimental pulmonary fibrosis-induced pulmonary hypertension via attenuating epithelial-mesenchymal transition by suppressing Wnt/β-catenin signaling in vivo and in vitro
BackgroundThe co-occurrence of pulmonary hypertension (PH) in patients with pulmonary fibrosis (PF) is linked to a more unfavorable prognosis and increased mortality compared to PF cases without PH. Early intervention and comprehensive management are pivotal for improving survival outcomes. Proprote...
主要な著者: | , , , , , , |
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フォーマット: | 論文 |
言語: | English |
出版事項: |
Frontiers Media S.A.
2024-12-01
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シリーズ: | Frontiers in Medicine |
主題: | |
オンライン・アクセス: | https://www.frontiersin.org/articles/10.3389/fmed.2024.1509168/full |