Oxidative stress regulation and related metabolic pathways in epithelial–mesenchymal transition of breast cancer stem cells

Oxidative stress regulation and related metabolic pathways in epithelial–mesenchymal transition of breast cancer stem cells

Abstract Epithelial–mesenchymal transition (EMT) is a cell remodeling process in which epithelial cells undergo a reversible phenotype switch via the loss of adhesion capacity and acquisition of mesenchymal characteristics. In other words, EMT activation can increase invasiveness and metastatic prop...

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Bibliographic Details
Main Authors: Raheleh Farahzadi, Behnaz Valipour, Ezzatollah Fathi, Samaneh Pirmoradi, Ommoleila Molavi, Soheila Montazersaheb, Zohreh Sanaat
Format: Article
Language:English
Published: BMC 2023-11-01
Series:Stem Cell Research & Therapy
Subjects:
Epithelial–mesenchymal transition
Oxidative stress
Reactive oxygen species
Metabolic pathways
Transcription factors
Signaling pathways
Online Access:https://doi.org/10.1186/s13287-023-03571-6

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