Preserving the Integrity of Liposomes Prepared by Ethanol Injection upon Freeze-Drying: Insights from Combined Molecular Dynamics Simulations and Experimental Data
The freeze-drying of complex formulations, such as liposomes, is challenging, particularly if dispersions contain residual organic solvents. This work aimed to investigate the effects of possible protectants, namely sucrose, trehalose and/or poly(vinyl pyrrolidone) (PVP), on the main features of the...
| Auteurs principaux: | , , , , , |
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| Format: | Article |
| Langue: | English |
| Publié: |
MDPI AG
2020-06-01
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| Collection: | Pharmaceutics |
| Sujets: | |
| Accès en ligne: | https://www.mdpi.com/1999-4923/12/6/530 |