Synthesis and Cell Seeding Assessment of Novel Biphasic Nano Powder in the CaO–MgO–SiO2 System for Bone Implant Application

Objective(s): CaO–MgO–SiO2 system bioceramics possess good characteristics for hard tissue engineering applications. The aim of the study was to synthesize the nano powder by using a sol-gel method and evaluate of bioactivity in the cells culture. Methods: To characterize of powder X-ray diffraction...

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Main Authors: Kazem Marzban, Sayed Mahmood Rabiee
Format: Article
Language:English
Published: Iranian Society of Nanomedicine 2017-02-01
Series:Nanomedicine Research Journal
Subjects:
Online Access:http://www.nanomedicine-rj.com/article_22531_c9c63896cb6d369a92231e40a355d8bf.pdf
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author Kazem Marzban
Sayed Mahmood Rabiee
author_facet Kazem Marzban
Sayed Mahmood Rabiee
author_sort Kazem Marzban
collection DOAJ
description Objective(s): CaO–MgO–SiO2 system bioceramics possess good characteristics for hard tissue engineering applications. The aim of the study was to synthesize the nano powder by using a sol-gel method and evaluate of bioactivity in the cells culture. Methods: To characterize of powder X-ray diffraction (XRD), transmission electron microscopy (TEM) and to evaluate the bioactivity sample cell seeding and methylthiazol tetrazolium (MTT) assay were performed. Results: X-ray diffraction (XRD) analysis showed that the biphasic powder was obtained at 1300°C for 2 h by using a sol-gel method. Transmission electron microscopy (TEM) image showed that powder particle size was about 45 nm. Besides, cell culture results indicated that the percentage of viability values was increased by the extension of period. Conclusions: found that the sample is cytocompatible and has cell proliferation potential in culture medium. The present study demonstrates that, the biphasic CaO–MgO–SiO2 system can be used to achieve novel bioactive materials for bone implant application.
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spelling doaj.art-526649267d8a4bdfa734f3e7e5c5033b2022-12-21T21:09:47ZengIranian Society of NanomedicineNanomedicine Research Journal2476-34892476-71232017-02-01211610.22034/nmrj.2017.2253122531Synthesis and Cell Seeding Assessment of Novel Biphasic Nano Powder in the CaO–MgO–SiO2 System for Bone Implant ApplicationKazem Marzban0Sayed Mahmood Rabiee1Department of Biomaterials, Science and Research Branch, Islamic Azad University, Yazd, IranDepartment of Materials Engineering, Nanobiotechnology Research Group, Babol University of Technology, Babol, IranObjective(s): CaO–MgO–SiO2 system bioceramics possess good characteristics for hard tissue engineering applications. The aim of the study was to synthesize the nano powder by using a sol-gel method and evaluate of bioactivity in the cells culture. Methods: To characterize of powder X-ray diffraction (XRD), transmission electron microscopy (TEM) and to evaluate the bioactivity sample cell seeding and methylthiazol tetrazolium (MTT) assay were performed. Results: X-ray diffraction (XRD) analysis showed that the biphasic powder was obtained at 1300°C for 2 h by using a sol-gel method. Transmission electron microscopy (TEM) image showed that powder particle size was about 45 nm. Besides, cell culture results indicated that the percentage of viability values was increased by the extension of period. Conclusions: found that the sample is cytocompatible and has cell proliferation potential in culture medium. The present study demonstrates that, the biphasic CaO–MgO–SiO2 system can be used to achieve novel bioactive materials for bone implant application.http://www.nanomedicine-rj.com/article_22531_c9c63896cb6d369a92231e40a355d8bf.pdfNano powderCaO–MgO–SiO2 systemBone implants application
spellingShingle Kazem Marzban
Sayed Mahmood Rabiee
Synthesis and Cell Seeding Assessment of Novel Biphasic Nano Powder in the CaO–MgO–SiO2 System for Bone Implant Application
Nanomedicine Research Journal
Nano powder
CaO–MgO–SiO2 system
Bone implants application
title Synthesis and Cell Seeding Assessment of Novel Biphasic Nano Powder in the CaO–MgO–SiO2 System for Bone Implant Application
title_full Synthesis and Cell Seeding Assessment of Novel Biphasic Nano Powder in the CaO–MgO–SiO2 System for Bone Implant Application
title_fullStr Synthesis and Cell Seeding Assessment of Novel Biphasic Nano Powder in the CaO–MgO–SiO2 System for Bone Implant Application
title_full_unstemmed Synthesis and Cell Seeding Assessment of Novel Biphasic Nano Powder in the CaO–MgO–SiO2 System for Bone Implant Application
title_short Synthesis and Cell Seeding Assessment of Novel Biphasic Nano Powder in the CaO–MgO–SiO2 System for Bone Implant Application
title_sort synthesis and cell seeding assessment of novel biphasic nano powder in the cao mgo sio2 system for bone implant application
topic Nano powder
CaO–MgO–SiO2 system
Bone implants application
url http://www.nanomedicine-rj.com/article_22531_c9c63896cb6d369a92231e40a355d8bf.pdf
work_keys_str_mv AT kazemmarzban synthesisandcellseedingassessmentofnovelbiphasicnanopowderinthecaomgosio2systemforboneimplantapplication
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