Synthesis and Cell Seeding Assessment of Novel Biphasic Nano Powder in the CaO–MgO–SiO2 System for Bone Implant Application
Objective(s): CaO–MgO–SiO2 system bioceramics possess good characteristics for hard tissue engineering applications. The aim of the study was to synthesize the nano powder by using a sol-gel method and evaluate of bioactivity in the cells culture. Methods: To characterize of powder X-ray diffraction...
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Format: | Article |
Language: | English |
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Iranian Society of Nanomedicine
2017-02-01
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Series: | Nanomedicine Research Journal |
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Online Access: | http://www.nanomedicine-rj.com/article_22531_c9c63896cb6d369a92231e40a355d8bf.pdf |
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author | Kazem Marzban Sayed Mahmood Rabiee |
author_facet | Kazem Marzban Sayed Mahmood Rabiee |
author_sort | Kazem Marzban |
collection | DOAJ |
description | Objective(s): CaO–MgO–SiO2 system bioceramics possess good characteristics for hard tissue engineering applications. The aim of the study was to synthesize the nano powder by using a sol-gel method and evaluate of bioactivity in the cells culture. Methods: To characterize of powder X-ray diffraction (XRD), transmission electron microscopy (TEM) and to evaluate the bioactivity sample cell seeding and methylthiazol tetrazolium (MTT) assay were performed. Results: X-ray diffraction (XRD) analysis showed that the biphasic powder was obtained at 1300°C for 2 h by using a sol-gel method. Transmission electron microscopy (TEM) image showed that powder particle size was about 45 nm. Besides, cell culture results indicated that the percentage of viability values was increased by the extension of period. Conclusions: found that the sample is cytocompatible and has cell proliferation potential in culture medium. The present study demonstrates that, the biphasic CaO–MgO–SiO2 system can be used to achieve novel bioactive materials for bone implant application. |
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id | doaj.art-526649267d8a4bdfa734f3e7e5c5033b |
institution | Directory Open Access Journal |
issn | 2476-3489 2476-7123 |
language | English |
last_indexed | 2024-12-18T11:23:46Z |
publishDate | 2017-02-01 |
publisher | Iranian Society of Nanomedicine |
record_format | Article |
series | Nanomedicine Research Journal |
spelling | doaj.art-526649267d8a4bdfa734f3e7e5c5033b2022-12-21T21:09:47ZengIranian Society of NanomedicineNanomedicine Research Journal2476-34892476-71232017-02-01211610.22034/nmrj.2017.2253122531Synthesis and Cell Seeding Assessment of Novel Biphasic Nano Powder in the CaO–MgO–SiO2 System for Bone Implant ApplicationKazem Marzban0Sayed Mahmood Rabiee1Department of Biomaterials, Science and Research Branch, Islamic Azad University, Yazd, IranDepartment of Materials Engineering, Nanobiotechnology Research Group, Babol University of Technology, Babol, IranObjective(s): CaO–MgO–SiO2 system bioceramics possess good characteristics for hard tissue engineering applications. The aim of the study was to synthesize the nano powder by using a sol-gel method and evaluate of bioactivity in the cells culture. Methods: To characterize of powder X-ray diffraction (XRD), transmission electron microscopy (TEM) and to evaluate the bioactivity sample cell seeding and methylthiazol tetrazolium (MTT) assay were performed. Results: X-ray diffraction (XRD) analysis showed that the biphasic powder was obtained at 1300°C for 2 h by using a sol-gel method. Transmission electron microscopy (TEM) image showed that powder particle size was about 45 nm. Besides, cell culture results indicated that the percentage of viability values was increased by the extension of period. Conclusions: found that the sample is cytocompatible and has cell proliferation potential in culture medium. The present study demonstrates that, the biphasic CaO–MgO–SiO2 system can be used to achieve novel bioactive materials for bone implant application.http://www.nanomedicine-rj.com/article_22531_c9c63896cb6d369a92231e40a355d8bf.pdfNano powderCaO–MgO–SiO2 systemBone implants application |
spellingShingle | Kazem Marzban Sayed Mahmood Rabiee Synthesis and Cell Seeding Assessment of Novel Biphasic Nano Powder in the CaO–MgO–SiO2 System for Bone Implant Application Nanomedicine Research Journal Nano powder CaO–MgO–SiO2 system Bone implants application |
title | Synthesis and Cell Seeding Assessment of Novel Biphasic Nano Powder in the CaO–MgO–SiO2 System for Bone Implant Application |
title_full | Synthesis and Cell Seeding Assessment of Novel Biphasic Nano Powder in the CaO–MgO–SiO2 System for Bone Implant Application |
title_fullStr | Synthesis and Cell Seeding Assessment of Novel Biphasic Nano Powder in the CaO–MgO–SiO2 System for Bone Implant Application |
title_full_unstemmed | Synthesis and Cell Seeding Assessment of Novel Biphasic Nano Powder in the CaO–MgO–SiO2 System for Bone Implant Application |
title_short | Synthesis and Cell Seeding Assessment of Novel Biphasic Nano Powder in the CaO–MgO–SiO2 System for Bone Implant Application |
title_sort | synthesis and cell seeding assessment of novel biphasic nano powder in the cao mgo sio2 system for bone implant application |
topic | Nano powder CaO–MgO–SiO2 system Bone implants application |
url | http://www.nanomedicine-rj.com/article_22531_c9c63896cb6d369a92231e40a355d8bf.pdf |
work_keys_str_mv | AT kazemmarzban synthesisandcellseedingassessmentofnovelbiphasicnanopowderinthecaomgosio2systemforboneimplantapplication AT sayedmahmoodrabiee synthesisandcellseedingassessmentofnovelbiphasicnanopowderinthecaomgosio2systemforboneimplantapplication |