Pain in rheumatoid arthritis: a critical review
Patients with rheumatoid arthritis (RA) are frequently afflicted by pain, which may be caused by joint inflammation (leading to structural joint damage) or secondary osteoarthritis, and may be increased by central sensitisation. Non-inflammatory pain may also confuse the assessment of disease activi...
| Main Authors: | , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
PAGEPress Publications
2014-06-01
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| Series: | Reumatismo |
| Subjects: | |
| Online Access: | http://www.reumatismo.org/index.php/reuma/article/view/760 |
| _version_ | 1828365156004921344 |
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| author | P. Sarzi-Puttini F. Salaffi M. Di Franco L. Bazzichi G. Cassisi R. Casale M. Cazzola S. Stisi M. Battellino F. Atzeni |
| author_facet | P. Sarzi-Puttini F. Salaffi M. Di Franco L. Bazzichi G. Cassisi R. Casale M. Cazzola S. Stisi M. Battellino F. Atzeni |
| author_sort | P. Sarzi-Puttini |
| collection | DOAJ |
| description | Patients with rheumatoid arthritis (RA) are frequently afflicted by pain, which may be caused by joint inflammation (leading to structural joint damage) or secondary osteoarthritis, and may be increased by central sensitisation. Non-inflammatory pain may also confuse the assessment of disease activity, and so the aim of treatment is not only to combat inflammatory disease, but also relieve painful symptoms. In order to ensure effective treatment stratification, it is necessary to record a patients medical history in detail, perform a physical examination, and objectively assess synovitis and joint damage. The management of pain requires various approaches that include pharmacological analgesia and biological and non-biological treatments. Although joint replacement surgery can significantly improve RA-related pain, it may only be available to patients with the most severe advanced disease. |
| first_indexed | 2024-04-14T05:26:17Z |
| format | Article |
| id | doaj.art-5268fa19ede54b8cb27b7941737dcf10 |
| institution | Directory Open Access Journal |
| issn | 0048-7449 2240-2683 |
| language | English |
| last_indexed | 2024-04-14T05:26:17Z |
| publishDate | 2014-06-01 |
| publisher | PAGEPress Publications |
| record_format | Article |
| series | Reumatismo |
| spelling | doaj.art-5268fa19ede54b8cb27b7941737dcf102022-12-22T02:09:57ZengPAGEPress PublicationsReumatismo0048-74492240-26832014-06-01661182710.4081/reumatismo.2014.760637Pain in rheumatoid arthritis: a critical reviewP. Sarzi-Puttini0F. Salaffi1M. Di Franco2L. Bazzichi3G. Cassisi4R. Casale5M. Cazzola6S. Stisi7M. Battellino8F. Atzeni9Rheumatology Unit, L. Sacco University Hospital, MilanReumatology Department, Polytechnic University of MarcheReumatology Department, La Sapienza University, RomeDepartment of Internal Medicine, Division of Rheumatology, S. Chiara Hospital, University of PisaRheumatology Branch, Specialist Outpatients’ Department, BellunoDepartment of Clinical Neurophysiology and Pain Rehabilitation Unit, IRCCS Foundation Salvatore Maugeri, Scientific Institute of Montescano (PV)U.O.C. Rehabilitative Medicine, A.O. “Ospedale di Circolo”, Saronno (VA)A.O. r.n. “G. Rummo” BeneventoRheumatology Unit, L. Sacco University Hospital, MilanRheumatology Unit, L. Sacco University Hospital, MilanPatients with rheumatoid arthritis (RA) are frequently afflicted by pain, which may be caused by joint inflammation (leading to structural joint damage) or secondary osteoarthritis, and may be increased by central sensitisation. Non-inflammatory pain may also confuse the assessment of disease activity, and so the aim of treatment is not only to combat inflammatory disease, but also relieve painful symptoms. In order to ensure effective treatment stratification, it is necessary to record a patients medical history in detail, perform a physical examination, and objectively assess synovitis and joint damage. The management of pain requires various approaches that include pharmacological analgesia and biological and non-biological treatments. Although joint replacement surgery can significantly improve RA-related pain, it may only be available to patients with the most severe advanced disease.http://www.reumatismo.org/index.php/reuma/article/view/760Rheumatoid arthritis, Pain, Central sensitization, Analgesics. |
| spellingShingle | P. Sarzi-Puttini F. Salaffi M. Di Franco L. Bazzichi G. Cassisi R. Casale M. Cazzola S. Stisi M. Battellino F. Atzeni Pain in rheumatoid arthritis: a critical review Reumatismo Rheumatoid arthritis, Pain, Central sensitization, Analgesics. |
| title | Pain in rheumatoid arthritis: a critical review |
| title_full | Pain in rheumatoid arthritis: a critical review |
| title_fullStr | Pain in rheumatoid arthritis: a critical review |
| title_full_unstemmed | Pain in rheumatoid arthritis: a critical review |
| title_short | Pain in rheumatoid arthritis: a critical review |
| title_sort | pain in rheumatoid arthritis a critical review |
| topic | Rheumatoid arthritis, Pain, Central sensitization, Analgesics. |
| url | http://www.reumatismo.org/index.php/reuma/article/view/760 |
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