THE GENES ASSOCIATED WITH LIPID METABOLISM DISORDERS AND WITH BLOOD PRESSURE REGULATION, AND PSYCHOVEGETATIVE CHANGES IN THE YOUNG ALMOST HEALTHY PERSONS
Aim. To assess the relation of polymorphism of the genes APOC3, PON1, AGT, AGTR1 and psychovegetative disorders in young, relatively healthy persons.Material and methods. Totally, 75 healthy volunteers included, white race, aged 20-25 y.o. Psychovegetative status was assessed with tests for panic...
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| Format: | Article |
| Language: | Russian |
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«SILICEA-POLIGRAF» LLC
2016-12-01
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| Series: | Кардиоваскулярная терапия и профилактика |
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| Online Access: | https://cardiovascular.elpub.ru/jour/article/view/516 |
| _version_ | 1797882455911301120 |
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| author | Yu. G. Shvarts A. Yu. Elkina N. S. Akimova T. V. Martynovich E. A. Fedotov |
| author_facet | Yu. G. Shvarts A. Yu. Elkina N. S. Akimova T. V. Martynovich E. A. Fedotov |
| author_sort | Yu. G. Shvarts |
| collection | DOAJ |
| description | Aim. To assess the relation of polymorphism of the genes APOC3, PON1, AGT, AGTR1 and psychovegetative disorders in young, relatively healthy persons.Material and methods. Totally, 75 healthy volunteers included, white race, aged 20-25 y.o. Psychovegetative status was assessed with tests for panic attacks revealing, anxiety level assessment, as with the questionnaire for vegetovascular dystony. The inclusion criteria was organic pathology of cardiovascular and central nervous system. Genes polymorphism was identified with the method of pyrosequencing of desoxyribonucleic acid with the genetic analysis equipment “PyroMark Q24”Results. The presence of vegetovascular dystony, panic attacks and increased level of anxiety was mostly associated with the presence of T polymorphism -482 C>T gene APOC3, allele М polymorphism L55M А>Т gene PON1 and allele А — polymorphism А1666С А>С gene AGTR1. Conclusion. There is relation of genes polymorphism playing role in lipids metabolism and arterial pressure regulation, with psychovegetative status of the young, relatively healthy persons. |
| first_indexed | 2024-04-10T03:36:07Z |
| format | Article |
| id | doaj.art-526cf831fba64057868b397a3a3b27bd |
| institution | Directory Open Access Journal |
| issn | 1728-8800 2619-0125 |
| language | Russian |
| last_indexed | 2024-04-10T03:36:07Z |
| publishDate | 2016-12-01 |
| publisher | «SILICEA-POLIGRAF» LLC |
| record_format | Article |
| series | Кардиоваскулярная терапия и профилактика |
| spelling | doaj.art-526cf831fba64057868b397a3a3b27bd2023-03-13T07:23:25Zrus«SILICEA-POLIGRAF» LLCКардиоваскулярная терапия и профилактика1728-88002619-01252016-12-01156535710.15829/1728-8800-2016-6-53-57398THE GENES ASSOCIATED WITH LIPID METABOLISM DISORDERS AND WITH BLOOD PRESSURE REGULATION, AND PSYCHOVEGETATIVE CHANGES IN THE YOUNG ALMOST HEALTHY PERSONSYu. G. Shvarts0A. Yu. Elkina1N. S. Akimova2T. V. Martynovich3E. A. Fedotov4Саратовский государственный медицинский университет имени В. И. РазумовскогоСаратовский государственный медицинский университет имени В. И. РазумовскогоСаратовский государственный медицинский университет имени В. И. РазумовскогоСаратовский государственный медицинский университет имени В. И. РазумовскогоМедицинский Di центр, ОООAim. To assess the relation of polymorphism of the genes APOC3, PON1, AGT, AGTR1 and psychovegetative disorders in young, relatively healthy persons.Material and methods. Totally, 75 healthy volunteers included, white race, aged 20-25 y.o. Psychovegetative status was assessed with tests for panic attacks revealing, anxiety level assessment, as with the questionnaire for vegetovascular dystony. The inclusion criteria was organic pathology of cardiovascular and central nervous system. Genes polymorphism was identified with the method of pyrosequencing of desoxyribonucleic acid with the genetic analysis equipment “PyroMark Q24”Results. The presence of vegetovascular dystony, panic attacks and increased level of anxiety was mostly associated with the presence of T polymorphism -482 C>T gene APOC3, allele М polymorphism L55M А>Т gene PON1 and allele А — polymorphism А1666С А>С gene AGTR1. Conclusion. There is relation of genes polymorphism playing role in lipids metabolism and arterial pressure regulation, with psychovegetative status of the young, relatively healthy persons.https://cardiovascular.elpub.ru/jour/article/view/516генетический полиморфизмпанические атакивегетативная дистония |
| spellingShingle | Yu. G. Shvarts A. Yu. Elkina N. S. Akimova T. V. Martynovich E. A. Fedotov THE GENES ASSOCIATED WITH LIPID METABOLISM DISORDERS AND WITH BLOOD PRESSURE REGULATION, AND PSYCHOVEGETATIVE CHANGES IN THE YOUNG ALMOST HEALTHY PERSONS Кардиоваскулярная терапия и профилактика генетический полиморфизм панические атаки вегетативная дистония |
| title | THE GENES ASSOCIATED WITH LIPID METABOLISM DISORDERS AND WITH BLOOD PRESSURE REGULATION, AND PSYCHOVEGETATIVE CHANGES IN THE YOUNG ALMOST HEALTHY PERSONS |
| title_full | THE GENES ASSOCIATED WITH LIPID METABOLISM DISORDERS AND WITH BLOOD PRESSURE REGULATION, AND PSYCHOVEGETATIVE CHANGES IN THE YOUNG ALMOST HEALTHY PERSONS |
| title_fullStr | THE GENES ASSOCIATED WITH LIPID METABOLISM DISORDERS AND WITH BLOOD PRESSURE REGULATION, AND PSYCHOVEGETATIVE CHANGES IN THE YOUNG ALMOST HEALTHY PERSONS |
| title_full_unstemmed | THE GENES ASSOCIATED WITH LIPID METABOLISM DISORDERS AND WITH BLOOD PRESSURE REGULATION, AND PSYCHOVEGETATIVE CHANGES IN THE YOUNG ALMOST HEALTHY PERSONS |
| title_short | THE GENES ASSOCIATED WITH LIPID METABOLISM DISORDERS AND WITH BLOOD PRESSURE REGULATION, AND PSYCHOVEGETATIVE CHANGES IN THE YOUNG ALMOST HEALTHY PERSONS |
| title_sort | genes associated with lipid metabolism disorders and with blood pressure regulation and psychovegetative changes in the young almost healthy persons |
| topic | генетический полиморфизм панические атаки вегетативная дистония |
| url | https://cardiovascular.elpub.ru/jour/article/view/516 |
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