Phenotypic traits of mesenchymal stem cell sheets fabricated by temperature-responsive cell culture plate: structural characteristics of MSC sheets

Abstract Background In most stem cell therapy strategies reported to date, stem cells are introduced to damaged tissue sites to repair and regenerate the original tissue structure and function. MSC therapeutic efficacies are inconsistent, largely attributed to transplanted MSC difficulties both in e...

Full description

Bibliographic Details
Main Authors: Mitsuyoshi Nakao, Kyungsook Kim, Kenichi Nagase, David W. Grainger, Hideko Kanazawa, Teruo Okano
Format: Article
Language:English
Published: BMC 2019-11-01
Series:Stem Cell Research & Therapy
Online Access:https://doi.org/10.1186/s13287-019-1431-6