Vascular ultrasound measures before pregnancy and pregnancy complications: A prospective cohort study
Objectives: To examine the relationship between pre-pregnancy indicators of cardiovascular risk and pregnancy complications and outcomes. Study design: Data from 359 female participants in the Cardiovascular Risk in Young Finns Study were linked with the national birth registry. Flow-mediated dilata...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Taylor & Francis Group
2017-01-01
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| Series: | Hypertension in Pregnancy |
| Subjects: | |
| Online Access: | http://dx.doi.org/10.1080/10641955.2016.1237643 |
| _version_ | 1827814496746340352 |
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| author | Emily W. Harville Markus Juonala Jorma S. A. Viikari Mika Kähönen Olli T. Raitakari |
| author_facet | Emily W. Harville Markus Juonala Jorma S. A. Viikari Mika Kähönen Olli T. Raitakari |
| author_sort | Emily W. Harville |
| collection | DOAJ |
| description | Objectives: To examine the relationship between pre-pregnancy indicators of cardiovascular risk and pregnancy complications and outcomes. Study design: Data from 359 female participants in the Cardiovascular Risk in Young Finns Study were linked with the national birth registry. Flow-mediated dilatation (FMD; maximum change in the left brachial artery diameter after rest and hyperemia); carotid intima-media thickness (IMT); Young’s elastic modulus (YEM); and carotid artery distensibility (Cdist) at the visit prior to the pregnancy were examined as predictors of hypertensive disorders, birthweight, and gestational age using multivariable linear regression with adjustment for confounders (age, BMI, smoking, and socioeconomic status). Results: No relations were seen between FMD, IMT, or the stiffness indices, and hypertensive disorders. Higher pre-pregnancy FMD was associated with lower gestational age, while increased Cdist was associated with reduced birthweight-for-gestational-age. Conclusions: Some cardiovascular ultrasound measures of pre-pregnancy may predict pregnancy complications, but the association is likely to be small. |
| first_indexed | 2024-03-11T23:46:59Z |
| format | Article |
| id | doaj.art-52739ad2d5c74211ac09895029dff10f |
| institution | Directory Open Access Journal |
| issn | 1064-1955 1525-6065 |
| language | English |
| last_indexed | 2024-03-11T23:46:59Z |
| publishDate | 2017-01-01 |
| publisher | Taylor & Francis Group |
| record_format | Article |
| series | Hypertension in Pregnancy |
| spelling | doaj.art-52739ad2d5c74211ac09895029dff10f2023-09-19T09:24:41ZengTaylor & Francis GroupHypertension in Pregnancy1064-19551525-60652017-01-01361535810.1080/10641955.2016.12376431237643Vascular ultrasound measures before pregnancy and pregnancy complications: A prospective cohort studyEmily W. Harville0Markus Juonala1Jorma S. A. Viikari2Mika Kähönen3Olli T. Raitakari4Tulane University School of Public HealthTurku University HospitalTurku University HospitalTampere University Hospital and University of TampereTurku University HospitalObjectives: To examine the relationship between pre-pregnancy indicators of cardiovascular risk and pregnancy complications and outcomes. Study design: Data from 359 female participants in the Cardiovascular Risk in Young Finns Study were linked with the national birth registry. Flow-mediated dilatation (FMD; maximum change in the left brachial artery diameter after rest and hyperemia); carotid intima-media thickness (IMT); Young’s elastic modulus (YEM); and carotid artery distensibility (Cdist) at the visit prior to the pregnancy were examined as predictors of hypertensive disorders, birthweight, and gestational age using multivariable linear regression with adjustment for confounders (age, BMI, smoking, and socioeconomic status). Results: No relations were seen between FMD, IMT, or the stiffness indices, and hypertensive disorders. Higher pre-pregnancy FMD was associated with lower gestational age, while increased Cdist was associated with reduced birthweight-for-gestational-age. Conclusions: Some cardiovascular ultrasound measures of pre-pregnancy may predict pregnancy complications, but the association is likely to be small.http://dx.doi.org/10.1080/10641955.2016.1237643birthprematurebrachial arteryhypertensionpregnancy-inducedinfantlow birth weightultrasonography |
| spellingShingle | Emily W. Harville Markus Juonala Jorma S. A. Viikari Mika Kähönen Olli T. Raitakari Vascular ultrasound measures before pregnancy and pregnancy complications: A prospective cohort study Hypertension in Pregnancy birth premature brachial artery hypertension pregnancy-induced infant low birth weight ultrasonography |
| title | Vascular ultrasound measures before pregnancy and pregnancy complications: A prospective cohort study |
| title_full | Vascular ultrasound measures before pregnancy and pregnancy complications: A prospective cohort study |
| title_fullStr | Vascular ultrasound measures before pregnancy and pregnancy complications: A prospective cohort study |
| title_full_unstemmed | Vascular ultrasound measures before pregnancy and pregnancy complications: A prospective cohort study |
| title_short | Vascular ultrasound measures before pregnancy and pregnancy complications: A prospective cohort study |
| title_sort | vascular ultrasound measures before pregnancy and pregnancy complications a prospective cohort study |
| topic | birth premature brachial artery hypertension pregnancy-induced infant low birth weight ultrasonography |
| url | http://dx.doi.org/10.1080/10641955.2016.1237643 |
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