The ESCRT-Related ATPase Vps4 Is Modulated by Interferon during Herpes Simplex Virus 1 Infection

The ESCRT-Related ATPase Vps4 Is Modulated by Interferon during Herpes Simplex Virus 1 Infection

ABSTRACT Interferons (IFNs) and autophagy are critical neuronal defenses against viral infection. IFNs alter neuronal autophagy by promoting the accumulation of IFN-dependent LC3-decorated autophagic structures, termed LC3 clusters. Here, we analyzed LC3 clusters in sensory ganglia following herpes...

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Bibliographic Details
Main Authors: Jorge Ruben Cabrera, Richard Manivanh, Brian J. North, David A. Leib
Format: Article
Language:English
Published: American Society for Microbiology 2019-04-01
Series:mBio
Subjects:
ESCRT
autophagy
herpes simplex virus
interferons
neuroimmunology
Online Access:https://journals.asm.org/doi/10.1128/mBio.02567-18

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