Fuzheng Nizeng Decoction regulated ferroptosis and endoplasmic reticulum stress in the treatment of gastric precancerous lesions: A mechanistic study based on metabolomics coupled with transcriptomics
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| Main Authors: | , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Frontiers Media S.A.
2022-11-01
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| Series: | Frontiers in Pharmacology |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fphar.2022.1066244/full |
| _version_ | 1811179843665002496 |
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| author | Ying-Ming Chu Ting-Xin Wang Xiao-Fen Jia Yao Yang Zong-Ming Shi Guang-Hui Cui Qiu-Yue Huang Hui Ye Xue-Zhi Zhang |
| author_facet | Ying-Ming Chu Ting-Xin Wang Xiao-Fen Jia Yao Yang Zong-Ming Shi Guang-Hui Cui Qiu-Yue Huang Hui Ye Xue-Zhi Zhang |
| author_sort | Ying-Ming Chu |
| collection | DOAJ |
| description | Graphical Abstract |
| first_indexed | 2024-04-11T06:40:21Z |
| format | Article |
| id | doaj.art-527892e33a07449ba3c399137dd2e6ef |
| institution | Directory Open Access Journal |
| issn | 1663-9812 |
| language | English |
| last_indexed | 2024-04-11T06:40:21Z |
| publishDate | 2022-11-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Pharmacology |
| spelling | doaj.art-527892e33a07449ba3c399137dd2e6ef2022-12-22T04:39:33ZengFrontiers Media S.A.Frontiers in Pharmacology1663-98122022-11-011310.3389/fphar.2022.10662441066244Fuzheng Nizeng Decoction regulated ferroptosis and endoplasmic reticulum stress in the treatment of gastric precancerous lesions: A mechanistic study based on metabolomics coupled with transcriptomicsYing-Ming Chu0Ting-Xin Wang1Xiao-Fen Jia2Yao Yang3Zong-Ming Shi4Guang-Hui Cui5Qiu-Yue Huang6Hui Ye7Xue-Zhi Zhang8Department of Integrated Traditional Chinese and Western Medicine, Peking University First Hospital, Institute of Integrated Traditional Chinese and Western Medicine, Peking University, Beijing, ChinaInstitute (College) of Integrative Medicine, Dalian Medical University, Dalian, ChinaDepartment of Integrated Traditional Chinese and Western Medicine, Peking University First Hospital, Institute of Integrated Traditional Chinese and Western Medicine, Peking University, Beijing, ChinaDepartment of Integrated Traditional Chinese and Western Medicine, Peking University First Hospital, Institute of Integrated Traditional Chinese and Western Medicine, Peking University, Beijing, ChinaDepartment of Integrated Traditional Chinese and Western Medicine, Peking University First Hospital, Institute of Integrated Traditional Chinese and Western Medicine, Peking University, Beijing, ChinaDepartment of Integrated Traditional Chinese and Western Medicine, Peking University First Hospital, Institute of Integrated Traditional Chinese and Western Medicine, Peking University, Beijing, ChinaDepartment of Integrated Traditional Chinese and Western Medicine, Peking University First Hospital, Institute of Integrated Traditional Chinese and Western Medicine, Peking University, Beijing, ChinaDepartment of Integrated Traditional Chinese and Western Medicine, Peking University First Hospital, Institute of Integrated Traditional Chinese and Western Medicine, Peking University, Beijing, ChinaDepartment of Integrated Traditional Chinese and Western Medicine, Peking University First Hospital, Institute of Integrated Traditional Chinese and Western Medicine, Peking University, Beijing, ChinaGraphical Abstracthttps://www.frontiersin.org/articles/10.3389/fphar.2022.1066244/fullferroptosis regulationnatural medicinegastric precancerous lesionsendoplasmic reticulum stressmetabolismtranscriptomics |
| spellingShingle | Ying-Ming Chu Ting-Xin Wang Xiao-Fen Jia Yao Yang Zong-Ming Shi Guang-Hui Cui Qiu-Yue Huang Hui Ye Xue-Zhi Zhang Fuzheng Nizeng Decoction regulated ferroptosis and endoplasmic reticulum stress in the treatment of gastric precancerous lesions: A mechanistic study based on metabolomics coupled with transcriptomics Frontiers in Pharmacology ferroptosis regulation natural medicine gastric precancerous lesions endoplasmic reticulum stress metabolism transcriptomics |
| title | Fuzheng Nizeng Decoction regulated ferroptosis and endoplasmic reticulum stress in the treatment of gastric precancerous lesions: A mechanistic study based on metabolomics coupled with transcriptomics |
| title_full | Fuzheng Nizeng Decoction regulated ferroptosis and endoplasmic reticulum stress in the treatment of gastric precancerous lesions: A mechanistic study based on metabolomics coupled with transcriptomics |
| title_fullStr | Fuzheng Nizeng Decoction regulated ferroptosis and endoplasmic reticulum stress in the treatment of gastric precancerous lesions: A mechanistic study based on metabolomics coupled with transcriptomics |
| title_full_unstemmed | Fuzheng Nizeng Decoction regulated ferroptosis and endoplasmic reticulum stress in the treatment of gastric precancerous lesions: A mechanistic study based on metabolomics coupled with transcriptomics |
| title_short | Fuzheng Nizeng Decoction regulated ferroptosis and endoplasmic reticulum stress in the treatment of gastric precancerous lesions: A mechanistic study based on metabolomics coupled with transcriptomics |
| title_sort | fuzheng nizeng decoction regulated ferroptosis and endoplasmic reticulum stress in the treatment of gastric precancerous lesions a mechanistic study based on metabolomics coupled with transcriptomics |
| topic | ferroptosis regulation natural medicine gastric precancerous lesions endoplasmic reticulum stress metabolism transcriptomics |
| url | https://www.frontiersin.org/articles/10.3389/fphar.2022.1066244/full |
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