Pharmacological Preconditioning: Role of Opioid Peptides

The review deals with the mechanisms of action of opioids and the synthetic analogue of endogenous leuenkephaline dalargin. It discusses the relation of delta-opioid receptors to the phenomenon of pharmacological preconditioning that may explain the universal cytoprotective properties of dalargin ob...

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Main Authors: V. V. Likhvantsev, O. A. Grebenchikov, A. A. Shaposhnikov, K. Yu. Borisov, R. A. Cherpakov, N. M. Shulgina
Format: Article
Language:English
Published: Federal Research and Clinical Center of Intensive Care Medicine and Rehabilitology, Moscow, Russia 2012-06-01
Series:Общая реаниматология
Online Access:https://www.reanimatology.com/rmt/article/view/221
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author V. V. Likhvantsev
O. A. Grebenchikov
A. A. Shaposhnikov
K. Yu. Borisov
R. A. Cherpakov
N. M. Shulgina
author_facet V. V. Likhvantsev
O. A. Grebenchikov
A. A. Shaposhnikov
K. Yu. Borisov
R. A. Cherpakov
N. M. Shulgina
author_sort V. V. Likhvantsev
collection DOAJ
description The review deals with the mechanisms of action of opioids and the synthetic analogue of endogenous leuenkephaline dalargin. It discusses the relation of delta-opioid receptors to the phenomenon of pharmacological preconditioning that may explain the universal cytoprotective properties of dalargin observed in clinical observations. Key words: opioids, opioid receptors, pharmacological preconditioning, cytoprotection, dalargin.
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publisher Federal Research and Clinical Center of Intensive Care Medicine and Rehabilitology, Moscow, Russia
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spelling doaj.art-5278b98b5f9942cf959af8cde4c1990f2023-03-13T09:32:52ZengFederal Research and Clinical Center of Intensive Care Medicine and Rehabilitology, Moscow, RussiaОбщая реаниматология1813-97792411-71102012-06-018310.15360/1813-9779-2012-3-51221Pharmacological Preconditioning: Role of Opioid PeptidesV. V. LikhvantsevO. A. GrebenchikovA. A. ShaposhnikovK. Yu. BorisovR. A. CherpakovN. M. ShulginaThe review deals with the mechanisms of action of opioids and the synthetic analogue of endogenous leuenkephaline dalargin. It discusses the relation of delta-opioid receptors to the phenomenon of pharmacological preconditioning that may explain the universal cytoprotective properties of dalargin observed in clinical observations. Key words: opioids, opioid receptors, pharmacological preconditioning, cytoprotection, dalargin.https://www.reanimatology.com/rmt/article/view/221
spellingShingle V. V. Likhvantsev
O. A. Grebenchikov
A. A. Shaposhnikov
K. Yu. Borisov
R. A. Cherpakov
N. M. Shulgina
Pharmacological Preconditioning: Role of Opioid Peptides
Общая реаниматология
title Pharmacological Preconditioning: Role of Opioid Peptides
title_full Pharmacological Preconditioning: Role of Opioid Peptides
title_fullStr Pharmacological Preconditioning: Role of Opioid Peptides
title_full_unstemmed Pharmacological Preconditioning: Role of Opioid Peptides
title_short Pharmacological Preconditioning: Role of Opioid Peptides
title_sort pharmacological preconditioning role of opioid peptides
url https://www.reanimatology.com/rmt/article/view/221
work_keys_str_mv AT vvlikhvantsev pharmacologicalpreconditioningroleofopioidpeptides
AT oagrebenchikov pharmacologicalpreconditioningroleofopioidpeptides
AT aashaposhnikov pharmacologicalpreconditioningroleofopioidpeptides
AT kyuborisov pharmacologicalpreconditioningroleofopioidpeptides
AT racherpakov pharmacologicalpreconditioningroleofopioidpeptides
AT nmshulgina pharmacologicalpreconditioningroleofopioidpeptides