Attenuation of Hyperlipidemia by Medicinal Formulations of <i>Emblica officinalis</i> Synergized with Nanotechnological Approaches
The ayurvedic herb <i>Emblica officinalis</i> (<i>E. officinalis</i>) is a gift to mankind to acquire a healthy lifestyle. It has great therapeutic and nutritional importance. <i>Emblica officinalis</i>, also known as Indian gooseberry or Amla, is a member of the...
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MDPI AG
2023-01-01
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| Series: | Bioengineering |
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| Online Access: | https://www.mdpi.com/2306-5354/10/1/64 |
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| author | Puttasiddaiah Rachitha Krupashree Krishnaswamy Renal Antoinette Lazar Vijai Kumar Gupta Baskaran Stephen Inbaraj Vinay Basavegowda Raghavendra Minaxi Sharma Kandi Sridhar |
| author_facet | Puttasiddaiah Rachitha Krupashree Krishnaswamy Renal Antoinette Lazar Vijai Kumar Gupta Baskaran Stephen Inbaraj Vinay Basavegowda Raghavendra Minaxi Sharma Kandi Sridhar |
| author_sort | Puttasiddaiah Rachitha |
| collection | DOAJ |
| description | The ayurvedic herb <i>Emblica officinalis</i> (<i>E. officinalis</i>) is a gift to mankind to acquire a healthy lifestyle. It has great therapeutic and nutritional importance. <i>Emblica officinalis</i>, also known as Indian gooseberry or Amla, is a member of the Euphorbiaceae family. Amla is beneficial for treating illnesses in all its forms. The most crucial component is a fruit, which is also the most common. It is used frequently in Indian medicine as a restorative, diuretic, liver tonic, refrigerant, stomachic, laxative, antipyretic, hair tonic, ulcer preventive, and for the common cold and fever. Hyperlipidemia is also known as high cholesterol or an increase in one or more lipid-containing blood proteins. Various phytocompounds, including polyphenols, vitamins, amino acids, fixed oils, and flavonoids, are present in the various parts of <i>E. officinalis</i>. <i>E. officinalis</i> has been linked to a variety of pharmacological effects in earlier studies, including hepatoprotective, immunomodulatory, antimicrobial, radioprotective, and hyperlipidemic effects. The amla-derived active ingredients and food products nevertheless encounter challenges such as instability and interactions with other food matrices. Considering the issue from this perspective, food component nanoencapsulation is a young and cutting-edge field for controlled and targeted delivery with a range of preventative activities. The nanoformulation of <i>E. officinalis</i> facilitates the release of active components or food ingredients, increased bioaccessibility, enhanced therapeutic activities, and digestion in the human body. Accordingly, the current review provides a summary of the phytoconstituents of <i>E. officinalis</i>, pharmacological actions detailing the plant <i>E. officinalis</i>’s traditional uses, and especially hyperlipidemic activity. Correspondingly, the article describes the uses of nanotechnology in amla therapeutics and functional ingredients. |
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| format | Article |
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| issn | 2306-5354 |
| language | English |
| last_indexed | 2024-03-09T13:33:05Z |
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| spelling | doaj.art-527db26d79c24cc9970a009460c152ea2023-11-30T21:14:57ZengMDPI AGBioengineering2306-53542023-01-011016410.3390/bioengineering10010064Attenuation of Hyperlipidemia by Medicinal Formulations of <i>Emblica officinalis</i> Synergized with Nanotechnological ApproachesPuttasiddaiah Rachitha0Krupashree Krishnaswamy1Renal Antoinette Lazar2Vijai Kumar Gupta3Baskaran Stephen Inbaraj4Vinay Basavegowda Raghavendra5Minaxi Sharma6Kandi Sridhar7P.G. Department of Biotechnology, Teresian College, Siddarthanagar, Mysuru 570011, IndiaBiochemistry Department, Central Food Technological Research Institute, Mysore 570006, IndiaP.G. Department of Biotechnology, Teresian College, Siddarthanagar, Mysuru 570011, IndiaBiorefining and Advanced Materials Research Center, Scotland’s Rural College (SRUC), Edinburgh EH9 3JG, UKDepartment of Food Science, Fu Jen Catholic University, New Taipei City 242 05, TaiwanP.G. Department of Biotechnology, Teresian College, Siddarthanagar, Mysuru 570011, IndiaHaute Ecole Provinciale de Hainaut-Condorcet, 7800 Ath, BelgiumDepartment of Food Technology, Koneru Lakshmaiah Education Foundation Deemed to be University, Vaddeswaram 522502, IndiaThe ayurvedic herb <i>Emblica officinalis</i> (<i>E. officinalis</i>) is a gift to mankind to acquire a healthy lifestyle. It has great therapeutic and nutritional importance. <i>Emblica officinalis</i>, also known as Indian gooseberry or Amla, is a member of the Euphorbiaceae family. Amla is beneficial for treating illnesses in all its forms. The most crucial component is a fruit, which is also the most common. It is used frequently in Indian medicine as a restorative, diuretic, liver tonic, refrigerant, stomachic, laxative, antipyretic, hair tonic, ulcer preventive, and for the common cold and fever. Hyperlipidemia is also known as high cholesterol or an increase in one or more lipid-containing blood proteins. Various phytocompounds, including polyphenols, vitamins, amino acids, fixed oils, and flavonoids, are present in the various parts of <i>E. officinalis</i>. <i>E. officinalis</i> has been linked to a variety of pharmacological effects in earlier studies, including hepatoprotective, immunomodulatory, antimicrobial, radioprotective, and hyperlipidemic effects. The amla-derived active ingredients and food products nevertheless encounter challenges such as instability and interactions with other food matrices. Considering the issue from this perspective, food component nanoencapsulation is a young and cutting-edge field for controlled and targeted delivery with a range of preventative activities. The nanoformulation of <i>E. officinalis</i> facilitates the release of active components or food ingredients, increased bioaccessibility, enhanced therapeutic activities, and digestion in the human body. Accordingly, the current review provides a summary of the phytoconstituents of <i>E. officinalis</i>, pharmacological actions detailing the plant <i>E. officinalis</i>’s traditional uses, and especially hyperlipidemic activity. Correspondingly, the article describes the uses of nanotechnology in amla therapeutics and functional ingredients.https://www.mdpi.com/2306-5354/10/1/64<i>Emblica officinalis</i>phytochemicalshyperlipidemiapharmacologynanoformulation |
| spellingShingle | Puttasiddaiah Rachitha Krupashree Krishnaswamy Renal Antoinette Lazar Vijai Kumar Gupta Baskaran Stephen Inbaraj Vinay Basavegowda Raghavendra Minaxi Sharma Kandi Sridhar Attenuation of Hyperlipidemia by Medicinal Formulations of <i>Emblica officinalis</i> Synergized with Nanotechnological Approaches Bioengineering <i>Emblica officinalis</i> phytochemicals hyperlipidemia pharmacology nanoformulation |
| title | Attenuation of Hyperlipidemia by Medicinal Formulations of <i>Emblica officinalis</i> Synergized with Nanotechnological Approaches |
| title_full | Attenuation of Hyperlipidemia by Medicinal Formulations of <i>Emblica officinalis</i> Synergized with Nanotechnological Approaches |
| title_fullStr | Attenuation of Hyperlipidemia by Medicinal Formulations of <i>Emblica officinalis</i> Synergized with Nanotechnological Approaches |
| title_full_unstemmed | Attenuation of Hyperlipidemia by Medicinal Formulations of <i>Emblica officinalis</i> Synergized with Nanotechnological Approaches |
| title_short | Attenuation of Hyperlipidemia by Medicinal Formulations of <i>Emblica officinalis</i> Synergized with Nanotechnological Approaches |
| title_sort | attenuation of hyperlipidemia by medicinal formulations of i emblica officinalis i synergized with nanotechnological approaches |
| topic | <i>Emblica officinalis</i> phytochemicals hyperlipidemia pharmacology nanoformulation |
| url | https://www.mdpi.com/2306-5354/10/1/64 |
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