Neurological disorders and immunosuppression in kidney transplant patients. Preliminary study
Background: Neurological disorders in kidney transplant patients may be related to several factors, including high toxicity to the use of immunosuppressive drugs. Objective: To find out whether there was association between neurological complications and immunosuppression in a sample of patients wh...
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Colegio Mexicano de Inmunología Clínica y Alergia, A.C.
2016-08-01
|
| Series: | Revista Alergia México |
| Subjects: | |
| Online Access: | http://revistaalergia.mx/ojs/index.php/ram/article/view/160 |
| _version_ | 1797714153904799744 |
|---|---|
| author | Chasity Romero-Vázquez Alain R. Rodríguez-Orozco Raúl Leal-Cantú Christian Cortés-Rojo |
| author_facet | Chasity Romero-Vázquez Alain R. Rodríguez-Orozco Raúl Leal-Cantú Christian Cortés-Rojo |
| author_sort | Chasity Romero-Vázquez |
| collection | DOAJ |
| description | Background: Neurological disorders in kidney transplant patients may be related to several factors, including high toxicity to the use of immunosuppressive drugs.
Objective: To find out whether there was association between neurological complications and immunosuppression in a sample of patients who received renal transplantation.
Methods: Cross-sectional study in which 121 renal transplant patients participated, of which 22 (18%) had neurological disorders, χ2 was used to analyze the relation between neurological disorders and comorbidity such as diabetes mellitus and hypertension and time of immunosuppressant use. A significance level of p <0.05 was accepted for all determinations
Results: Of the subjects studied, 13 were male (59%) and nine female (41%). The mean age of the patients included in the study was 33 ± 12 years. 59% of neurological disorders occurred between six months and five years after patients had received the transplant. Neurological alterations found were: tremor (7.4%), dizziness (4.1%), peripheral neuropathy (3.3%), headache (2.4%), and decreased strength (0.8%).
Conclusion: No statistically significant association was found between neurological disorders and immunosuppressant use, or between them and the duration of immunosuppression. |
| first_indexed | 2024-03-12T07:47:43Z |
| format | Article |
| id | doaj.art-527f95e0696a4ffa908f1cf0f8953307 |
| institution | Directory Open Access Journal |
| issn | 0002-5151 2448-9190 |
| language | English |
| last_indexed | 2024-03-12T07:47:43Z |
| publishDate | 2016-08-01 |
| publisher | Colegio Mexicano de Inmunología Clínica y Alergia, A.C. |
| record_format | Article |
| series | Revista Alergia México |
| spelling | doaj.art-527f95e0696a4ffa908f1cf0f89533072023-09-02T20:50:24ZengColegio Mexicano de Inmunología Clínica y Alergia, A.C.Revista Alergia México0002-51512448-91902016-08-0163327828210.29262/ram.v63i3.160145Neurological disorders and immunosuppression in kidney transplant patients. Preliminary studyChasity Romero-Vázquez0Alain R. Rodríguez-Orozco1Raúl Leal-Cantú2Christian Cortés-Rojo3Universidad Michoacana de San Nicolás de Hidalgo, Facultad de Ciencias Médicas y Biológicas Dr. Ignacio Chávez, Morelia, MichoacánInstituto de Investigación Científica en Temas de Familia, Alergia e Inmunología, Morelia, MichoacánHospital General Dr. Miguel Silva. Morelia, MichoacánUniversidad Michoacana de San Nicolás de Hidalgo, Instituto de Investigaciones Químico Biológicas, Morelia, MichoacánBackground: Neurological disorders in kidney transplant patients may be related to several factors, including high toxicity to the use of immunosuppressive drugs. Objective: To find out whether there was association between neurological complications and immunosuppression in a sample of patients who received renal transplantation. Methods: Cross-sectional study in which 121 renal transplant patients participated, of which 22 (18%) had neurological disorders, χ2 was used to analyze the relation between neurological disorders and comorbidity such as diabetes mellitus and hypertension and time of immunosuppressant use. A significance level of p <0.05 was accepted for all determinations Results: Of the subjects studied, 13 were male (59%) and nine female (41%). The mean age of the patients included in the study was 33 ± 12 years. 59% of neurological disorders occurred between six months and five years after patients had received the transplant. Neurological alterations found were: tremor (7.4%), dizziness (4.1%), peripheral neuropathy (3.3%), headache (2.4%), and decreased strength (0.8%). Conclusion: No statistically significant association was found between neurological disorders and immunosuppressant use, or between them and the duration of immunosuppression.http://revistaalergia.mx/ojs/index.php/ram/article/view/160Alteraciones neurológicasTrasplante renalInmunosupresiónTiempo de inmunosupresiónCiclosporinaTacrolimus |
| spellingShingle | Chasity Romero-Vázquez Alain R. Rodríguez-Orozco Raúl Leal-Cantú Christian Cortés-Rojo Neurological disorders and immunosuppression in kidney transplant patients. Preliminary study Revista Alergia México Alteraciones neurológicas Trasplante renal Inmunosupresión Tiempo de inmunosupresión Ciclosporina Tacrolimus |
| title | Neurological disorders and immunosuppression in kidney transplant patients. Preliminary study |
| title_full | Neurological disorders and immunosuppression in kidney transplant patients. Preliminary study |
| title_fullStr | Neurological disorders and immunosuppression in kidney transplant patients. Preliminary study |
| title_full_unstemmed | Neurological disorders and immunosuppression in kidney transplant patients. Preliminary study |
| title_short | Neurological disorders and immunosuppression in kidney transplant patients. Preliminary study |
| title_sort | neurological disorders and immunosuppression in kidney transplant patients preliminary study |
| topic | Alteraciones neurológicas Trasplante renal Inmunosupresión Tiempo de inmunosupresión Ciclosporina Tacrolimus |
| url | http://revistaalergia.mx/ojs/index.php/ram/article/view/160 |
| work_keys_str_mv | AT chasityromerovazquez neurologicaldisordersandimmunosuppressioninkidneytransplantpatientspreliminarystudy AT alainrrodriguezorozco neurologicaldisordersandimmunosuppressioninkidneytransplantpatientspreliminarystudy AT raullealcantu neurologicaldisordersandimmunosuppressioninkidneytransplantpatientspreliminarystudy AT christiancortesrojo neurologicaldisordersandimmunosuppressioninkidneytransplantpatientspreliminarystudy |