Evolution of the immune landscape during progression of pancreatic intraductal papillary mucinous neoplasms to invasive cancer

Evolution of the immune landscape during progression of pancreatic intraductal papillary mucinous neoplasms to invasive cancer

ABSTRACT: Background: Intraductal papillary mucinous neoplasms (IPMNs) are precursor lesions of pancreatic cancer, which is characterized by an immunosuppressive microenvironment. Yet, the spatial distribution of the immune infiltrate and how it changes during IPMN progression is just beginning to...

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Bibliographic Details
Main Authors: Susanne Roth, Katharina Zamzow, Matthias M. Gaida, Mathias Heikenwälder, Christine Tjaden, Ulf Hinz, Promita Bose, Christoph W. Michalski, Thilo Hackert
Format: Article
Language:English
Published: Elsevier 2020-04-01
Series:EBioMedicine
Online Access:http://www.sciencedirect.com/science/article/pii/S235239642030089X

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