First report of carbapenem-resistant Providencia stuartii in Saudi Arabia
We present the case of 31-year-old man who developed hospital-acquired pneumonia in the intensive care unit. Pathogens were identified to be carbapenem-resistant isolates of Providencia stuartii and Klebsiella pneumoniae. The patient was treated with an extended infusion of double-dose meropenem (ta...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2018-11-01
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| Series: | New Microbes and New Infections |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2052297518300878 |
| _version_ | 1818957422499201024 |
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| author | M. Abdallah R. Alhababi N. Alqudah B. Aldyyat A. Alharthy |
| author_facet | M. Abdallah R. Alhababi N. Alqudah B. Aldyyat A. Alharthy |
| author_sort | M. Abdallah |
| collection | DOAJ |
| description | We present the case of 31-year-old man who developed hospital-acquired pneumonia in the intensive care unit. Pathogens were identified to be carbapenem-resistant isolates of Providencia stuartii and Klebsiella pneumoniae. The patient was treated with an extended infusion of double-dose meropenem (targeting the carbapenem-resistant P. stuartii) and colistin (targeting the carbapenem-resistant K. pneumoniae) for 2 weeks. The patient's disease responded well to the prescribed regimen; his chest X-ray became normal, and all other signs of infection subsided. To our knowledge, this is the first description of the emergence of carbapenem-resistant P. stuartii due to AmpC hyperproduction in Saudi Arabia. Keywords: Carbapenem resistant, extended infusion, meropenem, Providencia stuartii |
| first_indexed | 2024-12-20T11:09:36Z |
| format | Article |
| id | doaj.art-5285da6ef1424d5ca1f7726b503cd4b8 |
| institution | Directory Open Access Journal |
| issn | 2052-2975 |
| language | English |
| last_indexed | 2024-12-20T11:09:36Z |
| publishDate | 2018-11-01 |
| publisher | Elsevier |
| record_format | Article |
| series | New Microbes and New Infections |
| spelling | doaj.art-5285da6ef1424d5ca1f7726b503cd4b82022-12-21T19:42:49ZengElsevierNew Microbes and New Infections2052-29752018-11-0126107109First report of carbapenem-resistant Providencia stuartii in Saudi ArabiaM. Abdallah0R. Alhababi1N. Alqudah2B. Aldyyat3A. Alharthy4Pharmaceutical Care Services, King Saud Medical City, Riyadh, Saudi Arabia; Corresponding author: M. Abdallah, Pharmaceutical Care Services, King Saud Medical City, Riyadh, Saudi Arabia.Microbiology Department, King Saud Medical City, Riyadh, Saudi ArabiaPrevention and Control of Infection Administration, King Saud Medical City, Riyadh, Saudi ArabiaPharmacy Department, Dr. Sulaiman Al Habib Hospital (As-Suwaidi), Riyadh, Saudi ArabiaIntensive Care Unit, King Saud Medical City, Riyadh, Saudi ArabiaWe present the case of 31-year-old man who developed hospital-acquired pneumonia in the intensive care unit. Pathogens were identified to be carbapenem-resistant isolates of Providencia stuartii and Klebsiella pneumoniae. The patient was treated with an extended infusion of double-dose meropenem (targeting the carbapenem-resistant P. stuartii) and colistin (targeting the carbapenem-resistant K. pneumoniae) for 2 weeks. The patient's disease responded well to the prescribed regimen; his chest X-ray became normal, and all other signs of infection subsided. To our knowledge, this is the first description of the emergence of carbapenem-resistant P. stuartii due to AmpC hyperproduction in Saudi Arabia. Keywords: Carbapenem resistant, extended infusion, meropenem, Providencia stuartiihttp://www.sciencedirect.com/science/article/pii/S2052297518300878 |
| spellingShingle | M. Abdallah R. Alhababi N. Alqudah B. Aldyyat A. Alharthy First report of carbapenem-resistant Providencia stuartii in Saudi Arabia New Microbes and New Infections |
| title | First report of carbapenem-resistant Providencia stuartii in Saudi Arabia |
| title_full | First report of carbapenem-resistant Providencia stuartii in Saudi Arabia |
| title_fullStr | First report of carbapenem-resistant Providencia stuartii in Saudi Arabia |
| title_full_unstemmed | First report of carbapenem-resistant Providencia stuartii in Saudi Arabia |
| title_short | First report of carbapenem-resistant Providencia stuartii in Saudi Arabia |
| title_sort | first report of carbapenem resistant providencia stuartii in saudi arabia |
| url | http://www.sciencedirect.com/science/article/pii/S2052297518300878 |
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