Hereditary thrombophilia by factor V Leiden G1691A (heterozygous) and FII prothrombin G20210A (homozygous) mutations in a patient with ischemic cerebrovascular accident
ABSTRACT Mutations related to Factor V Leiden (G1691A) and prothrombin (G20210A) are associated with a significantly increased risk of venous thromboembolism. The identification of a patient affected by episodes of venous thromboembolism and carrier of G1691A (heterozygous) and G20210A (homozygous)...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Sociedade Brasileira de Patologia Clínica
2018-04-01
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| Series: | Jornal Brasileiro de Patologia e Medicina Laboratorial |
| Subjects: | |
| Online Access: | http://www.scielo.br/pdf/jbpml/v54n2/1676-2444-jbpml-54-02-0092.pdf |
| _version_ | 1798026361205424128 |
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| author | Leonardo G. P. Ruiz Maria Gabriela L. Oliveira Adriana L. Z. Ruiz Camila S. Daher Mauricio L. Nogueira |
| author_facet | Leonardo G. P. Ruiz Maria Gabriela L. Oliveira Adriana L. Z. Ruiz Camila S. Daher Mauricio L. Nogueira |
| author_sort | Leonardo G. P. Ruiz |
| collection | DOAJ |
| description | ABSTRACT Mutations related to Factor V Leiden (G1691A) and prothrombin (G20210A) are associated with a significantly increased risk of venous thromboembolism. The identification of a patient affected by episodes of venous thromboembolism and carrier of G1691A (heterozygous) and G20210A (homozygous) polymorphisms was determined by molecular tests [real-time polymerase chain reaction (PCR) methodology, Genexpert system] during attendance at the Base Hospital of São José do Rio Preto-SP, Brazil. |
| first_indexed | 2024-04-11T18:34:09Z |
| format | Article |
| id | doaj.art-528a70a10f46463db7b0375f7778edd2 |
| institution | Directory Open Access Journal |
| issn | 1678-4774 |
| language | English |
| last_indexed | 2024-04-11T18:34:09Z |
| publishDate | 2018-04-01 |
| publisher | Sociedade Brasileira de Patologia Clínica |
| record_format | Article |
| series | Jornal Brasileiro de Patologia e Medicina Laboratorial |
| spelling | doaj.art-528a70a10f46463db7b0375f7778edd22022-12-22T04:09:20ZengSociedade Brasileira de Patologia ClínicaJornal Brasileiro de Patologia e Medicina Laboratorial1678-47742018-04-01542929410.5935/1676-2444.20180016Hereditary thrombophilia by factor V Leiden G1691A (heterozygous) and FII prothrombin G20210A (homozygous) mutations in a patient with ischemic cerebrovascular accidentLeonardo G. P. RuizMaria Gabriela L. OliveiraAdriana L. Z. RuizCamila S. DaherMauricio L. NogueiraABSTRACT Mutations related to Factor V Leiden (G1691A) and prothrombin (G20210A) are associated with a significantly increased risk of venous thromboembolism. The identification of a patient affected by episodes of venous thromboembolism and carrier of G1691A (heterozygous) and G20210A (homozygous) polymorphisms was determined by molecular tests [real-time polymerase chain reaction (PCR) methodology, Genexpert system] during attendance at the Base Hospital of São José do Rio Preto-SP, Brazil.http://www.scielo.br/pdf/jbpml/v54n2/1676-2444-jbpml-54-02-0092.pdfthrombophiliamutationvenous thrombosis |
| spellingShingle | Leonardo G. P. Ruiz Maria Gabriela L. Oliveira Adriana L. Z. Ruiz Camila S. Daher Mauricio L. Nogueira Hereditary thrombophilia by factor V Leiden G1691A (heterozygous) and FII prothrombin G20210A (homozygous) mutations in a patient with ischemic cerebrovascular accident Jornal Brasileiro de Patologia e Medicina Laboratorial thrombophilia mutation venous thrombosis |
| title | Hereditary thrombophilia by factor V Leiden G1691A (heterozygous) and FII prothrombin G20210A (homozygous) mutations in a patient with ischemic cerebrovascular accident |
| title_full | Hereditary thrombophilia by factor V Leiden G1691A (heterozygous) and FII prothrombin G20210A (homozygous) mutations in a patient with ischemic cerebrovascular accident |
| title_fullStr | Hereditary thrombophilia by factor V Leiden G1691A (heterozygous) and FII prothrombin G20210A (homozygous) mutations in a patient with ischemic cerebrovascular accident |
| title_full_unstemmed | Hereditary thrombophilia by factor V Leiden G1691A (heterozygous) and FII prothrombin G20210A (homozygous) mutations in a patient with ischemic cerebrovascular accident |
| title_short | Hereditary thrombophilia by factor V Leiden G1691A (heterozygous) and FII prothrombin G20210A (homozygous) mutations in a patient with ischemic cerebrovascular accident |
| title_sort | hereditary thrombophilia by factor v leiden g1691a heterozygous and fii prothrombin g20210a homozygous mutations in a patient with ischemic cerebrovascular accident |
| topic | thrombophilia mutation venous thrombosis |
| url | http://www.scielo.br/pdf/jbpml/v54n2/1676-2444-jbpml-54-02-0092.pdf |
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