Tumor Necrosis Factor Alpha Induces Reactivation of Human Cytomegalovirus Independently of Myeloid Cell Differentiation following Posttranscriptional Establishment of Latency

Tumor Necrosis Factor Alpha Induces Reactivation of Human Cytomegalovirus Independently of Myeloid Cell Differentiation following Posttranscriptional Establishment of Latency

ABSTRACT We used the Kasumi-3 model to study human cytomegalovirus (HCMV) latency and reactivation in myeloid progenitor cells. Kasumi-3 cells were infected with HCMV strain TB40/Ewt-GFP, flow sorted for green fluorescent protein-positive (GFP+) cells, and cultured for various times to monitor estab...

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Bibliographic Details
Main Authors: Eleonora Forte, Suchitra Swaminathan, Mark W. Schroeder, Jeong Yeon Kim, Scott S. Terhune, Mary Hummel
Format: Article
Language:English
Published: American Society for Microbiology 2018-11-01
Series:mBio
Subjects:
cytomegalovirus
latency
reactivation
Online Access:https://journals.asm.org/doi/10.1128/mBio.01560-18

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