Multiorgan tuberculosis

Tuberculosis is an unusual infectious disease because of the latent period between the infection and the appearance of the disease may be prolonged for many weeks, months, or years as it is in case of the secondary tuberculosis. Tuberculosis in organs other than the lung has been observed for many y...

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Main Authors: Đokić Milomir, Bojić Ivanko, Mikić Dragan, Mladenović Ljubiša, Begović Vesna, Kuprešanin Srđan, Mirović Veljko, Dimitrijević Jovan
Format: Article
Language:English
Published: Military Health Department, Ministry of Defance, Serbia 2002-01-01
Series:Vojnosanitetski Pregled
Subjects:
Online Access:http://www.doiserbia.nb.rs/img/doi/0042-8450/2002/0042-84500203317D.pdf
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author Đokić Milomir
Bojić Ivanko
Mikić Dragan
Mladenović Ljubiša
Begović Vesna
Kuprešanin Srđan
Mirović Veljko
Dimitrijević Jovan
author_facet Đokić Milomir
Bojić Ivanko
Mikić Dragan
Mladenović Ljubiša
Begović Vesna
Kuprešanin Srđan
Mirović Veljko
Dimitrijević Jovan
author_sort Đokić Milomir
collection DOAJ
description Tuberculosis is an unusual infectious disease because of the latent period between the infection and the appearance of the disease may be prolonged for many weeks, months, or years as it is in case of the secondary tuberculosis. Tuberculosis in organs other than the lung has been observed for many years but has not always been recognized as tuberculosis, and it has been given many names. Extrapulmonary tuberculosis gained new importance, because it represented a progressively greater proportion of new cases. Multiple extrapulmonary sites were reported rarely except for one anatomical site, which was reported frequently. Extrapulmonary rates increase with age, so there are marked differences in age in specific rate patterns among the sites. Extrapulmonary tuberculosis occurred in respiratory organs other than lung, such as lymphatic, urogenital, and central nervous system, abdominal, osteoarticular, as well as tuberculosis of other organs such as skin, pericardium and endocrine glands. This case was reported to analyse clinical, morphologic and laboratory characteristics, method of diagnosis and the outcome in patients with multiorgan tuberculosis in order to explore the factors which might contribute to the decision making, concerning these forms of tuberculosis. Recent knowledge of pathogenesis was summarized as well as clinical presentation and the effects of cytokines produced by T lymphocytes and cellular population on antimycobacterial immune defences, and also susceptibility to tuberculosis. Mortality remains high and the treatment should start as soon as tuberculosis is suspected.
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spelling doaj.art-528b9a31a3ed418e822993fa3e33c86f2022-12-21T19:54:39ZengMilitary Health Department, Ministry of Defance, SerbiaVojnosanitetski Pregled0042-84502002-01-0159331732410.2298/VSP0203317DMultiorgan tuberculosisĐokić MilomirBojić IvankoMikić DraganMladenović LjubišaBegović VesnaKuprešanin SrđanMirović VeljkoDimitrijević JovanTuberculosis is an unusual infectious disease because of the latent period between the infection and the appearance of the disease may be prolonged for many weeks, months, or years as it is in case of the secondary tuberculosis. Tuberculosis in organs other than the lung has been observed for many years but has not always been recognized as tuberculosis, and it has been given many names. Extrapulmonary tuberculosis gained new importance, because it represented a progressively greater proportion of new cases. Multiple extrapulmonary sites were reported rarely except for one anatomical site, which was reported frequently. Extrapulmonary rates increase with age, so there are marked differences in age in specific rate patterns among the sites. Extrapulmonary tuberculosis occurred in respiratory organs other than lung, such as lymphatic, urogenital, and central nervous system, abdominal, osteoarticular, as well as tuberculosis of other organs such as skin, pericardium and endocrine glands. This case was reported to analyse clinical, morphologic and laboratory characteristics, method of diagnosis and the outcome in patients with multiorgan tuberculosis in order to explore the factors which might contribute to the decision making, concerning these forms of tuberculosis. Recent knowledge of pathogenesis was summarized as well as clinical presentation and the effects of cytokines produced by T lymphocytes and cellular population on antimycobacterial immune defences, and also susceptibility to tuberculosis. Mortality remains high and the treatment should start as soon as tuberculosis is suspected.http://www.doiserbia.nb.rs/img/doi/0042-8450/2002/0042-84500203317D.pdftuberculosisdiagnosistuberculosis, pulmonarytuberculosis, hepatictuberculosis, renaltuberculosis, urogenitalantitubercular agentsimmune system
spellingShingle Đokić Milomir
Bojić Ivanko
Mikić Dragan
Mladenović Ljubiša
Begović Vesna
Kuprešanin Srđan
Mirović Veljko
Dimitrijević Jovan
Multiorgan tuberculosis
Vojnosanitetski Pregled
tuberculosis
diagnosis
tuberculosis, pulmonary
tuberculosis, hepatic
tuberculosis, renal
tuberculosis, urogenital
antitubercular agents
immune system
title Multiorgan tuberculosis
title_full Multiorgan tuberculosis
title_fullStr Multiorgan tuberculosis
title_full_unstemmed Multiorgan tuberculosis
title_short Multiorgan tuberculosis
title_sort multiorgan tuberculosis
topic tuberculosis
diagnosis
tuberculosis, pulmonary
tuberculosis, hepatic
tuberculosis, renal
tuberculosis, urogenital
antitubercular agents
immune system
url http://www.doiserbia.nb.rs/img/doi/0042-8450/2002/0042-84500203317D.pdf
work_keys_str_mv AT đokicmilomir multiorgantuberculosis
AT bojicivanko multiorgantuberculosis
AT mikicdragan multiorgantuberculosis
AT mladenovicljubisa multiorgantuberculosis
AT begovicvesna multiorgantuberculosis
AT kupresaninsrđan multiorgantuberculosis
AT mirovicveljko multiorgantuberculosis
AT dimitrijevicjovan multiorgantuberculosis