Multiorgan tuberculosis
Tuberculosis is an unusual infectious disease because of the latent period between the infection and the appearance of the disease may be prolonged for many weeks, months, or years as it is in case of the secondary tuberculosis. Tuberculosis in organs other than the lung has been observed for many y...
Main Authors: | , , , , , , , |
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Format: | Article |
Language: | English |
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Military Health Department, Ministry of Defance, Serbia
2002-01-01
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Series: | Vojnosanitetski Pregled |
Subjects: | |
Online Access: | http://www.doiserbia.nb.rs/img/doi/0042-8450/2002/0042-84500203317D.pdf |
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author | Đokić Milomir Bojić Ivanko Mikić Dragan Mladenović Ljubiša Begović Vesna Kuprešanin Srđan Mirović Veljko Dimitrijević Jovan |
author_facet | Đokić Milomir Bojić Ivanko Mikić Dragan Mladenović Ljubiša Begović Vesna Kuprešanin Srđan Mirović Veljko Dimitrijević Jovan |
author_sort | Đokić Milomir |
collection | DOAJ |
description | Tuberculosis is an unusual infectious disease because of the latent period between the infection and the appearance of the disease may be prolonged for many weeks, months, or years as it is in case of the secondary tuberculosis. Tuberculosis in organs other than the lung has been observed for many years but has not always been recognized as tuberculosis, and it has been given many names. Extrapulmonary tuberculosis gained new importance, because it represented a progressively greater proportion of new cases. Multiple extrapulmonary sites were reported rarely except for one anatomical site, which was reported frequently. Extrapulmonary rates increase with age, so there are marked differences in age in specific rate patterns among the sites. Extrapulmonary tuberculosis occurred in respiratory organs other than lung, such as lymphatic, urogenital, and central nervous system, abdominal, osteoarticular, as well as tuberculosis of other organs such as skin, pericardium and endocrine glands. This case was reported to analyse clinical, morphologic and laboratory characteristics, method of diagnosis and the outcome in patients with multiorgan tuberculosis in order to explore the factors which might contribute to the decision making, concerning these forms of tuberculosis. Recent knowledge of pathogenesis was summarized as well as clinical presentation and the effects of cytokines produced by T lymphocytes and cellular population on antimycobacterial immune defences, and also susceptibility to tuberculosis. Mortality remains high and the treatment should start as soon as tuberculosis is suspected. |
first_indexed | 2024-12-20T03:44:29Z |
format | Article |
id | doaj.art-528b9a31a3ed418e822993fa3e33c86f |
institution | Directory Open Access Journal |
issn | 0042-8450 |
language | English |
last_indexed | 2024-12-20T03:44:29Z |
publishDate | 2002-01-01 |
publisher | Military Health Department, Ministry of Defance, Serbia |
record_format | Article |
series | Vojnosanitetski Pregled |
spelling | doaj.art-528b9a31a3ed418e822993fa3e33c86f2022-12-21T19:54:39ZengMilitary Health Department, Ministry of Defance, SerbiaVojnosanitetski Pregled0042-84502002-01-0159331732410.2298/VSP0203317DMultiorgan tuberculosisĐokić MilomirBojić IvankoMikić DraganMladenović LjubišaBegović VesnaKuprešanin SrđanMirović VeljkoDimitrijević JovanTuberculosis is an unusual infectious disease because of the latent period between the infection and the appearance of the disease may be prolonged for many weeks, months, or years as it is in case of the secondary tuberculosis. Tuberculosis in organs other than the lung has been observed for many years but has not always been recognized as tuberculosis, and it has been given many names. Extrapulmonary tuberculosis gained new importance, because it represented a progressively greater proportion of new cases. Multiple extrapulmonary sites were reported rarely except for one anatomical site, which was reported frequently. Extrapulmonary rates increase with age, so there are marked differences in age in specific rate patterns among the sites. Extrapulmonary tuberculosis occurred in respiratory organs other than lung, such as lymphatic, urogenital, and central nervous system, abdominal, osteoarticular, as well as tuberculosis of other organs such as skin, pericardium and endocrine glands. This case was reported to analyse clinical, morphologic and laboratory characteristics, method of diagnosis and the outcome in patients with multiorgan tuberculosis in order to explore the factors which might contribute to the decision making, concerning these forms of tuberculosis. Recent knowledge of pathogenesis was summarized as well as clinical presentation and the effects of cytokines produced by T lymphocytes and cellular population on antimycobacterial immune defences, and also susceptibility to tuberculosis. Mortality remains high and the treatment should start as soon as tuberculosis is suspected.http://www.doiserbia.nb.rs/img/doi/0042-8450/2002/0042-84500203317D.pdftuberculosisdiagnosistuberculosis, pulmonarytuberculosis, hepatictuberculosis, renaltuberculosis, urogenitalantitubercular agentsimmune system |
spellingShingle | Đokić Milomir Bojić Ivanko Mikić Dragan Mladenović Ljubiša Begović Vesna Kuprešanin Srđan Mirović Veljko Dimitrijević Jovan Multiorgan tuberculosis Vojnosanitetski Pregled tuberculosis diagnosis tuberculosis, pulmonary tuberculosis, hepatic tuberculosis, renal tuberculosis, urogenital antitubercular agents immune system |
title | Multiorgan tuberculosis |
title_full | Multiorgan tuberculosis |
title_fullStr | Multiorgan tuberculosis |
title_full_unstemmed | Multiorgan tuberculosis |
title_short | Multiorgan tuberculosis |
title_sort | multiorgan tuberculosis |
topic | tuberculosis diagnosis tuberculosis, pulmonary tuberculosis, hepatic tuberculosis, renal tuberculosis, urogenital antitubercular agents immune system |
url | http://www.doiserbia.nb.rs/img/doi/0042-8450/2002/0042-84500203317D.pdf |
work_keys_str_mv | AT đokicmilomir multiorgantuberculosis AT bojicivanko multiorgantuberculosis AT mikicdragan multiorgantuberculosis AT mladenovicljubisa multiorgantuberculosis AT begovicvesna multiorgantuberculosis AT kupresaninsrđan multiorgantuberculosis AT mirovicveljko multiorgantuberculosis AT dimitrijevicjovan multiorgantuberculosis |