Agri-Food Waste from Apple, Pear, and Sugar Beet as a Source of Protective Bioactive Molecules for Endothelial Dysfunction and Its Major Complications
Endothelial damage is recognized as the initial step that precedes several cardiovascular diseases (CVD), such as atherosclerosis, hypertension, and coronary artery disease. It has been demonstrated that the best treatment for CVD is prevention, and, in the frame of a healthy lifestyle, the consumpt...
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| Format: | Article |
| Language: | English |
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MDPI AG
2022-09-01
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| Series: | Antioxidants |
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| Online Access: | https://www.mdpi.com/2076-3921/11/9/1786 |
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| author | Cristiana Caliceti Marco Malaguti Luisa Marracino Maria Cristina Barbalace Paola Rizzo Silvana Hrelia |
| author_facet | Cristiana Caliceti Marco Malaguti Luisa Marracino Maria Cristina Barbalace Paola Rizzo Silvana Hrelia |
| author_sort | Cristiana Caliceti |
| collection | DOAJ |
| description | Endothelial damage is recognized as the initial step that precedes several cardiovascular diseases (CVD), such as atherosclerosis, hypertension, and coronary artery disease. It has been demonstrated that the best treatment for CVD is prevention, and, in the frame of a healthy lifestyle, the consumption of vegetables, rich in bioactive molecules, appears effective at reducing the risk of CVD. In this context, the large amount of agri-food industry waste, considered a global problem due to its environmental and economic impact, represents an unexplored source of bioactive compounds. This review provides a summary regarding the possible exploitation of waste or by-products derived by the processing of three traditional Italian crops—apple, pear, and sugar beet—as a source of bioactive molecules to protect endothelial function. Particular attention has been given to the bioactive chemical profile of these pomaces and their efficacy in various pathological conditions related to endothelial dysfunction. The waste matrices of apple, pear, and sugar beet crops can represent promising starting material for producing “upcycled” products with functional applications, such as the prevention of endothelial dysfunction linked to cardiovascular diseases. |
| first_indexed | 2024-03-10T00:52:47Z |
| format | Article |
| id | doaj.art-528f05cd31624d678e61fe6eb0cdc2a4 |
| institution | Directory Open Access Journal |
| issn | 2076-3921 |
| language | English |
| last_indexed | 2024-03-10T00:52:47Z |
| publishDate | 2022-09-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Antioxidants |
| spelling | doaj.art-528f05cd31624d678e61fe6eb0cdc2a42023-11-23T14:48:52ZengMDPI AGAntioxidants2076-39212022-09-01119178610.3390/antiox11091786Agri-Food Waste from Apple, Pear, and Sugar Beet as a Source of Protective Bioactive Molecules for Endothelial Dysfunction and Its Major ComplicationsCristiana Caliceti0Marco Malaguti1Luisa Marracino2Maria Cristina Barbalace3Paola Rizzo4Silvana Hrelia5Department of Biomedical and Neuromotor Sciences, Alma Mater Studiorum, University of Bologna, 40126 Bologna, ItalyDepartment for Life Quality Studies, Alma Mater Studiorum, University of Bologna, 47921 Rimini, ItalyDepartment of Translational Medicine and Laboratory for Technologies of Advanced Therapies (LTTA), University of Ferrara, 44121 Ferrara, ItalyDepartment for Life Quality Studies, Alma Mater Studiorum, University of Bologna, 47921 Rimini, ItalyDepartment of Translational Medicine and Laboratory for Technologies of Advanced Therapies (LTTA), University of Ferrara, 44121 Ferrara, ItalyDepartment for Life Quality Studies, Alma Mater Studiorum, University of Bologna, 47921 Rimini, ItalyEndothelial damage is recognized as the initial step that precedes several cardiovascular diseases (CVD), such as atherosclerosis, hypertension, and coronary artery disease. It has been demonstrated that the best treatment for CVD is prevention, and, in the frame of a healthy lifestyle, the consumption of vegetables, rich in bioactive molecules, appears effective at reducing the risk of CVD. In this context, the large amount of agri-food industry waste, considered a global problem due to its environmental and economic impact, represents an unexplored source of bioactive compounds. This review provides a summary regarding the possible exploitation of waste or by-products derived by the processing of three traditional Italian crops—apple, pear, and sugar beet—as a source of bioactive molecules to protect endothelial function. Particular attention has been given to the bioactive chemical profile of these pomaces and their efficacy in various pathological conditions related to endothelial dysfunction. The waste matrices of apple, pear, and sugar beet crops can represent promising starting material for producing “upcycled” products with functional applications, such as the prevention of endothelial dysfunction linked to cardiovascular diseases.https://www.mdpi.com/2076-3921/11/9/1786endothelial dysfunctionagri-food wasteapplepearsugar beetcardiovascular diseases |
| spellingShingle | Cristiana Caliceti Marco Malaguti Luisa Marracino Maria Cristina Barbalace Paola Rizzo Silvana Hrelia Agri-Food Waste from Apple, Pear, and Sugar Beet as a Source of Protective Bioactive Molecules for Endothelial Dysfunction and Its Major Complications Antioxidants endothelial dysfunction agri-food waste apple pear sugar beet cardiovascular diseases |
| title | Agri-Food Waste from Apple, Pear, and Sugar Beet as a Source of Protective Bioactive Molecules for Endothelial Dysfunction and Its Major Complications |
| title_full | Agri-Food Waste from Apple, Pear, and Sugar Beet as a Source of Protective Bioactive Molecules for Endothelial Dysfunction and Its Major Complications |
| title_fullStr | Agri-Food Waste from Apple, Pear, and Sugar Beet as a Source of Protective Bioactive Molecules for Endothelial Dysfunction and Its Major Complications |
| title_full_unstemmed | Agri-Food Waste from Apple, Pear, and Sugar Beet as a Source of Protective Bioactive Molecules for Endothelial Dysfunction and Its Major Complications |
| title_short | Agri-Food Waste from Apple, Pear, and Sugar Beet as a Source of Protective Bioactive Molecules for Endothelial Dysfunction and Its Major Complications |
| title_sort | agri food waste from apple pear and sugar beet as a source of protective bioactive molecules for endothelial dysfunction and its major complications |
| topic | endothelial dysfunction agri-food waste apple pear sugar beet cardiovascular diseases |
| url | https://www.mdpi.com/2076-3921/11/9/1786 |
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