Higher levels of disease-related knowledge reduce medical acceleration in patients with inflammatory bowel disease.
BACKGROUND AND AIMS:The disease-related knowledge levels in patients with inflammatory bowel disease (IBD) are important because it could affect the self-management ability and adaptive coping strategies. We set out to determine whether higher levels of disease-related knowledge reduce medical accel...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Public Library of Science (PLoS)
2020-01-01
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| Series: | PLoS ONE |
| Online Access: | https://doi.org/10.1371/journal.pone.0233654 |
| _version_ | 1818933455624339456 |
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| author | Jihye Park Hyuk Yoon Cheol Min Shin Young Soo Park Nayoung Kim Dong Ho Lee |
| author_facet | Jihye Park Hyuk Yoon Cheol Min Shin Young Soo Park Nayoung Kim Dong Ho Lee |
| author_sort | Jihye Park |
| collection | DOAJ |
| description | BACKGROUND AND AIMS:The disease-related knowledge levels in patients with inflammatory bowel disease (IBD) are important because it could affect the self-management ability and adaptive coping strategies. We set out to determine whether higher levels of disease-related knowledge reduce medical acceleration. METHODS:We evaluated the levels of disease-related knowledge in all patients at the time of enrollment for SNUBH IBD cohort using the validated IBD-KNOW questionnaire. Clinical data were prospectively collected and the factors related to step-up therapy were analyzed. Step-up therapy was defined as the new use of corticosteroids, immunomodulators, or biologics after the enrollment. RESULTS:Between April 2017 and January 2019, 298 patients were enrolled (mean age, 39.8 years; males, 69.5%); 193 patients (64.8%) had ulcerative colitis and 105 (35.2%) had Crohn's disease. The mean disease duration was 35.8 months. During the mean follow-up of 14.7 months, 90 patients (30.2%) underwent step-up therapy and 208 (69.8%) underwent continuous therapy. The prevalence of continuous therapy increased with increasing IBD-KNOW scores (p for trend = 0.019). Cox proportional hazards analysis revealed that high IBD-KNOW scores (≥ 16) (hazards ratio [HR]: 0.498, 95% confidence interval [CI]: 0.276-0.897, p = 0.020) was negatively associated with the step-up therapy. CONCLUSIONS:Higher disease-related knowledge could reduce the requirement of step-up therapy in IBD. The IBD-KNOW score was independently predictive of step-up therapy. |
| first_indexed | 2024-12-20T04:48:39Z |
| format | Article |
| id | doaj.art-52960da21e8449b3b43f71b98f6f700c |
| institution | Directory Open Access Journal |
| issn | 1932-6203 |
| language | English |
| last_indexed | 2024-12-20T04:48:39Z |
| publishDate | 2020-01-01 |
| publisher | Public Library of Science (PLoS) |
| record_format | Article |
| series | PLoS ONE |
| spelling | doaj.art-52960da21e8449b3b43f71b98f6f700c2022-12-21T19:52:55ZengPublic Library of Science (PLoS)PLoS ONE1932-62032020-01-01156e023365410.1371/journal.pone.0233654Higher levels of disease-related knowledge reduce medical acceleration in patients with inflammatory bowel disease.Jihye ParkHyuk YoonCheol Min ShinYoung Soo ParkNayoung KimDong Ho LeeBACKGROUND AND AIMS:The disease-related knowledge levels in patients with inflammatory bowel disease (IBD) are important because it could affect the self-management ability and adaptive coping strategies. We set out to determine whether higher levels of disease-related knowledge reduce medical acceleration. METHODS:We evaluated the levels of disease-related knowledge in all patients at the time of enrollment for SNUBH IBD cohort using the validated IBD-KNOW questionnaire. Clinical data were prospectively collected and the factors related to step-up therapy were analyzed. Step-up therapy was defined as the new use of corticosteroids, immunomodulators, or biologics after the enrollment. RESULTS:Between April 2017 and January 2019, 298 patients were enrolled (mean age, 39.8 years; males, 69.5%); 193 patients (64.8%) had ulcerative colitis and 105 (35.2%) had Crohn's disease. The mean disease duration was 35.8 months. During the mean follow-up of 14.7 months, 90 patients (30.2%) underwent step-up therapy and 208 (69.8%) underwent continuous therapy. The prevalence of continuous therapy increased with increasing IBD-KNOW scores (p for trend = 0.019). Cox proportional hazards analysis revealed that high IBD-KNOW scores (≥ 16) (hazards ratio [HR]: 0.498, 95% confidence interval [CI]: 0.276-0.897, p = 0.020) was negatively associated with the step-up therapy. CONCLUSIONS:Higher disease-related knowledge could reduce the requirement of step-up therapy in IBD. The IBD-KNOW score was independently predictive of step-up therapy.https://doi.org/10.1371/journal.pone.0233654 |
| spellingShingle | Jihye Park Hyuk Yoon Cheol Min Shin Young Soo Park Nayoung Kim Dong Ho Lee Higher levels of disease-related knowledge reduce medical acceleration in patients with inflammatory bowel disease. PLoS ONE |
| title | Higher levels of disease-related knowledge reduce medical acceleration in patients with inflammatory bowel disease. |
| title_full | Higher levels of disease-related knowledge reduce medical acceleration in patients with inflammatory bowel disease. |
| title_fullStr | Higher levels of disease-related knowledge reduce medical acceleration in patients with inflammatory bowel disease. |
| title_full_unstemmed | Higher levels of disease-related knowledge reduce medical acceleration in patients with inflammatory bowel disease. |
| title_short | Higher levels of disease-related knowledge reduce medical acceleration in patients with inflammatory bowel disease. |
| title_sort | higher levels of disease related knowledge reduce medical acceleration in patients with inflammatory bowel disease |
| url | https://doi.org/10.1371/journal.pone.0233654 |
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